APAF1 抗体
(Apoptotic Peptidase Activating Factor 1 (APAF1))
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| APAF1 抗体 (AA 1-250) | 人 | 兔 Polyclonal |
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| APAF1 抗体 (AA 1138-1237) | 人 | 小鼠 Monoclonal |
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| APAF1 抗体 (AA 31-350) | 人 | 兔 Polyclonal |
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| APAF1 抗体 (AA 13-80) | 人 | 兔 Polyclonal |
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| APAF1 抗体 (AA 1201-1248) | 人 | 兔 Polyclonal |
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| APAF1 抗体 (Internal Region) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| APAF1 抗体 (C-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| APAF1 抗体 (AA 104-415) | 人 | 兔 Polyclonal |
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| APAF1 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| APAF1 抗体 (AA 260-340) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| APAF1 抗体 (AA 1-1205) | 人 | 兔 Polyclonal |
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| APAF1 抗体 (N-Term) | 人, 小鼠 | 大鼠 Monoclonal |
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| APAF1 抗体 (C-Term) | 人 | 兔 Polyclonal |
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| APAF1 抗体 (AA 1-1205) | 人 | 小鼠 Polyclonal |
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| APAF1 抗体 (C-Term) | 人, 大鼠 | 兔 Polyclonal |
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| APAF1 抗体 (AA 13-80) (AbBy Fluor® 350) | 人 | 兔 Polyclonal |
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| APAF1 抗体 (AA 13-80) (AbBy Fluor® 750) | 人 | 兔 Polyclonal |
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| APAF1 抗体 (AA 13-80) (Biotin) | 人 | 兔 Polyclonal |
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| APAF1 抗体 (AA 13-80) (AbBy Fluor® 594) | 人 | 兔 Polyclonal |
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| APAF1 抗体 (AA 13-80) (AbBy Fluor® 647) | 人 | 兔 Polyclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-250
Primary Antibody
- ELISA (ELISA: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 2H9A1
- 标记
- unconjugated
- 抗体亚型
- IgG2b
- 抗原表位
- AA 1138-1237
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 31-350
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- FACS (Flow Cytometry: 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 13-80
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- WB (Western Blotting: 所列应用)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
1 reference - 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1201-1248
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- Internal Region
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ELISA (ELISA: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 104-415
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- ELISA (ELISA: 所列应用)
- IF (Immunofluorescence: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 260-340
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-1205
Primary Antibody
- WB (Western Blotting: 所列应用)
- ELISA (ELISA: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 大鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 18H2
- 标记
- unconjugated
- 抗体亚型
- IgG2a kappa
- 抗原表位
- AA 1-97, N-Term
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-1205
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- 适用
- 人, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- C-Term
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 350
- 抗体亚型
- IgG
- 抗原表位
- AA 13-80
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 750
- 抗体亚型
- IgG
- 抗原表位
- AA 13-80
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- Biotin
- 抗体亚型
- IgG
- 抗原表位
- AA 13-80
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 594
- 抗体亚型
- IgG
- 抗原表位
- AA 13-80
Primary Antibody
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- AbBy Fluor® 647
- 抗体亚型
- IgG
- 抗原表位
- AA 13-80
Latest Publications for our APAF1 抗体
: "Optimization of Experimental Variables Influencing Apoptosome Biosensor in HEK293T Cells." in: Sensors (Basel, Switzerland), Vol. 20, Issue 6, (2020) (PubMed).
: "A new split-luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation." in: FEBS open bio, Vol. 9, Issue 7, pp. 1194-1203, (2020) (PubMed).
: "Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems." in: Archives of biochemistry and biophysics, Vol. 642, pp. 46-51, (2019) (PubMed).
: "LY333531, a PKCβ inhibitor, attenuates glomerular endothelial cell apoptosis in the early stage of mouse diabetic nephropathy via down-regulating swiprosin-1." in: Acta pharmacologica Sinica, Vol. 38, Issue 7, pp. 1009-1023, (2018) (PubMed).
: "Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma." in: Nature medicine, Vol. 21, Issue 9, pp. 1060-4, (2015) (PubMed).
: "Expression of SIRT1 and apoptosis-related proteins is predictive for lymph node metastasis and disease-free survival in luminal A breast cancer." in: Virchows Archiv : an international journal of pathology, Vol. 467, Issue 5, pp. 563-70, (2015) (PubMed).
: "Human interleukin 23 receptor induces cell apoptosis in mammalian cells by intrinsic mitochondrial pathway associated with the down-regulation of RAS/mitogen-activated protein kinase and signal ..." in: International journal of molecular sciences, Vol. 14, Issue 12, pp. 24656-69, (2014) (PubMed).
: "[Intralobar sequestration in elderly patient, report of a case]" in: Kyobu geka. The Japanese journal of thoracic surgery, Vol. 61, Issue 9, pp. 812-5, (2008) (PubMed).
: "Calcium blocks formation of apoptosome by preventing nucleotide exchange in Apaf-1." in: Molecular cell, Vol. 25, Issue 2, pp. 181-92, (2007) (PubMed).
: "Mechanical aspects of apoptosome assembly." in: Current opinion in cell biology, Vol. 18, Issue 6, pp. 677-84, (2006) (PubMed).
: "A new split-luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation." in: FEBS open bio, Vol. 9, Issue 7, pp. 1194-1203, (2020) (PubMed).
: "Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems." in: Archives of biochemistry and biophysics, Vol. 642, pp. 46-51, (2019) (PubMed).
: "LY333531, a PKCβ inhibitor, attenuates glomerular endothelial cell apoptosis in the early stage of mouse diabetic nephropathy via down-regulating swiprosin-1." in: Acta pharmacologica Sinica, Vol. 38, Issue 7, pp. 1009-1023, (2018) (PubMed).
: "Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma." in: Nature medicine, Vol. 21, Issue 9, pp. 1060-4, (2015) (PubMed).
: "Expression of SIRT1 and apoptosis-related proteins is predictive for lymph node metastasis and disease-free survival in luminal A breast cancer." in: Virchows Archiv : an international journal of pathology, Vol. 467, Issue 5, pp. 563-70, (2015) (PubMed).
: "Human interleukin 23 receptor induces cell apoptosis in mammalian cells by intrinsic mitochondrial pathway associated with the down-regulation of RAS/mitogen-activated protein kinase and signal ..." in: International journal of molecular sciences, Vol. 14, Issue 12, pp. 24656-69, (2014) (PubMed).
: "[Intralobar sequestration in elderly patient, report of a case]" in: Kyobu geka. The Japanese journal of thoracic surgery, Vol. 61, Issue 9, pp. 812-5, (2008) (PubMed).
: "Calcium blocks formation of apoptosome by preventing nucleotide exchange in Apaf-1." in: Molecular cell, Vol. 25, Issue 2, pp. 181-92, (2007) (PubMed).
: "Mechanical aspects of apoptosome assembly." in: Current opinion in cell biology, Vol. 18, Issue 6, pp. 677-84, (2006) (PubMed).
Aliases for APAF1 抗体
Death-associated APAF1-related killer (Dark) 抗体apoptotic peptidase activating factor 1 L homeolog (apaf1.L) 抗体
apoptotic peptidase activating factor 1 (apaf1) 抗体
apoptotic peptidase activating factor 1 (APAF1) 抗体
apoptotic peptidase activating factor 1 (Apaf1) 抗体
6230400I06Rik 抗体
anon-53Fa 抗体
Apaf-1 抗体
apaf-1 抗体
APAF-1 抗体
APAF1 抗体
Apaf1 抗体
apaf1 抗体
Apaf1l 抗体
arc 抗体
ARK 抗体
ark 抗体
CED4 抗体
CG6829 抗体
D-Apaf-1 抗体
dapaf 抗体
Dapaf-1 抗体
dAPAF-1 抗体
dApaf-1 抗体
dapaf-1 抗体
dApaf-1/DARK/HAC-1 抗体
Dapaf-1/HAC-1 抗体
dapaf-1L 抗体
dapaf-1S 抗体
dApaf1 抗体
DARK 抗体
Dark 抗体
dArk 抗体
dark 抗体
Dark/Apaf-I 抗体
dark/dapaf-1/hac-1 抗体
Dark/Dapaf-1/HAC1 抗体
Dark/Hac-1/dApaf-1 抗体
dark/hac-1/dapaf-1 抗体
Dark/Hac-1/dApaf1 抗体
Dmel\\CG6829 抗体
fog 抗体
Hac-1 抗体
hac-1 抗体
Hac-1/Dark 抗体
Hac1 抗体
hac1 抗体
l(2)SH0173 抗体
mKIAA0413 抗体
T1 抗体
zgc:136543 抗体
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