FAS 抗体
(2 references)Quick Overview for FAS 抗体 (ABIN969518)
抗原
See all FAS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- FAS Antibody
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human FAS expressed in E. Coli.
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亚型
- IgG1
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anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 150-250) antibody
FAS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 87-109), (N-Term) antibodyFAS 适用: 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 22-172) antibodyFAS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 22-169) antibodyFAS 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 21-170) antibodyFAS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibodyFAS 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2G3 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibodyFAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 5B4 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 1-335) antibodyFAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1B6 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 26-96) antibodyFAS 适用: 人 FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal FAS-3112 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 185-211) antibodyFAS 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "The Fas-mediated apoptotic pathway in cardiac myxoma." in: International journal of surgical pathology, Vol. 18, Issue 6, pp. 493-8, (2010) (PubMed).
: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).
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: "The Fas-mediated apoptotic pathway in cardiac myxoma." in: International journal of surgical pathology, Vol. 18, Issue 6, pp. 493-8, (2010) (PubMed).
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- FAS (TNF Receptor Superfamily, Member 6 (FAS))
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别名
- FAS
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背景
- The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.
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分子量
- 37.7 kDa
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基因ID
- 355
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UniProt
- P25445
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途径
- p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
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