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PAK2 抗体

This anti-PAK2 antibody is a 小鼠 单克隆 antibody detecting PAK2 in WB, ELISA, IHC 和 ICC. Suitable for 人 和 猴. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN969338
发货至: 中国

Quick Overview for PAK2 抗体 (ABIN969338)

抗原

See all PAK2 抗体
PAK2 (P21-Activated Kinase 2 (PAK2))

适用

  • 94
  • 47
  • 45
  • 2
  • 1
  • 1
人, 猴

宿主

  • 92
  • 3
小鼠

克隆类型

  • 81
  • 14
单克隆

标记

  • 62
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
This PAK2 antibody is un-conjugated

应用范围

  • 61
  • 49
  • 29
  • 16
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

克隆位点

3B5
  • 原理

    PAK2 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of PAK2 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Machuy, Campa, Thieck, Rudel: "c-Abl-binding protein interacts with p21-activated kinase 2 (PAK-2) to regulate PDGF-induced membrane ruffles." in: Journal of molecular biology, Vol. 370, Issue 4, pp. 620-32, (2007) (PubMed).

    Chu, Wu, Liao, Pardo, Zhao, Li, Mendenhall, Pali, Shen, Yu, Taylor, Aversa, Molineaux, Payan, Masuda: "A novel role for p21-activated protein kinase 2 in T cell activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 12, pp. 7324-34, (2004) (PubMed).

  • 抗原

    PAK2 (P21-Activated Kinase 2 (PAK2))

    别名

    PAK2

    背景

    PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.

    分子量

    61 kDa

    UniProt

    Q13177

    途径

    MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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