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NFKBIB 抗体

This anti-NFKBIB antibody is a 小鼠 单克隆 antibody detecting NFKBIB in WB 和 ELISA. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN969314
发货至: 中国

Quick Overview for NFKBIB 抗体 (ABIN969314)

抗原

See all NFKBIB 抗体
NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

适用

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宿主

  • 99
  • 9
小鼠

克隆类型

  • 91
  • 17
单克隆

标记

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  • 2
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This NFKBIB antibody is un-conjugated

应用范围

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  • 9
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Western Blotting (WB), ELISA

克隆位点

7B4
  • 原理

    NFKBIB Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human NFKBIB expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Yerges, Klei, Cauley, Roeder, Kammerer, Moffett, Ensrud, Nestlerode, Marshall, Hoffman, Lewis, Lang, Barrett-Connor, Ferrell, Orwoll, Zmuda: "High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, (2009) (PubMed).

    Chen, Vallee, Wu, Vu, Sondek, Ghosh: "Inhibition of NF-kappaB activity by IkappaBbeta in association with kappaB-Ras." in: Molecular and cellular biology, Vol. 24, Issue 7, pp. 3048-56, (2004) (PubMed).

    Abid, Schoots, Spokes, Wu, Mawhinney, Aird: "Vascular endothelial growth factor-mediated induction of manganese superoxide dismutase occurs through redox-dependent regulation of forkhead and IkappaB/NF-kappaB." in: The Journal of biological chemistry, Vol. 279, Issue 42, pp. 44030-8, (2004) (PubMed).

  • 抗原

    NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))

    别名

    NFKBIB

    背景

    Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined.

    分子量

    45 kDa

    基因ID

    4793

    UniProt

    Q15653

    途径

    NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
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