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NF-kB p65 抗体

Cited in 1 publication. This anti-NF-kB p65 antibody is a 小鼠 单克隆 antibody detecting NF-kB p65 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN969311
发货至: 中国
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Quick Overview for NF-kB p65 抗体 (ABIN969311)

抗原

See all NF-kB p65 (NFkBP65) 抗体
NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

适用

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人, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This NF-kB p65 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

6H7
  • 原理

    NF-κB p65 Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human NF-kappaB p65 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Yamit-Hezi, Nir, Wolstein, Dikstein: "Interaction of TAFII105 with selected p65/RelA dimers is associated with activation of subset of NF-kappa B genes." in: The Journal of biological chemistry, Vol. 275, Issue 24, pp. 18180-7, (2000) (PubMed).

  • 抗原

    NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

    别名

    NF-kappaB p65

    背景

    NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The heterodimeric RELA-NFKB1 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity.

    分子量

    65 kDa

    UniProt

    Q04206

    途径

    NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins
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