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NF-kB p65 抗体

NFkBP65 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6H7 unconjugated
产品编号 ABIN969311
发货至: 中国
  • 抗原 See all NF-kB p65 (NFkBP65) 抗体
    NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This NF-kB p65 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA
    原理
    NF-κB p65 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human NF-kappaB p65 expressed in E. Coli.
    克隆位点
    6H7
    亚型
    IgG1
    Top Product
    Discover our top product NFkBP65 Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Yamit-Hezi, Nir, Wolstein, Dikstein: "Interaction of TAFII105 with selected p65/RelA dimers is associated with activation of subset of NF-kappa B genes." in: The Journal of biological chemistry, Vol. 275, Issue 24, pp. 18180-7, (2000) (PubMed).

  • 抗原
    NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))
    别名
    NF-kappaB p65 (NFkBP65 产品)
    背景

    Description: NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The heterodimeric RELA-NFKB1 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity.

    Aliases: NFkappaB p65, p65, NFKB3, RELA

    分子量
    65kDa
    基因ID
    5970
    HGNC
    5970
    UniProt
    Q04206
    途径
    NF-kappaB Signaling, RTK signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins
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