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FOXD3 抗体

FOXD3 适用: 人, 小鼠, 猴 WB, ELISA 宿主: 小鼠 Monoclonal 5G9 unconjugated
产品编号 ABIN969152
发货至: 中国
  • 抗原 See all FOXD3 抗体
    FOXD3 (Forkhead Box D3 (FOXD3))
    适用
    • 31
    • 24
    • 5
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    人, 小鼠, 猴
    宿主
    • 29
    • 2
    • 1
    • 1
    小鼠
    克隆类型
    • 31
    • 2
    单克隆
    标记
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
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    This FOXD3 antibody is un-conjugated
    应用范围
    • 15
    • 13
    • 13
    • 13
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human FOXD3 expressed in E. coli.
    克隆位点
    5G9
    亚型
    IgG1
    Top Product
    Discover our top product FOXD3 Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Saleem, Banerjee-Basu, Berry, Baxevanis, Walter: "Analyses of the effects that disease-causing missense mutations have on the structure and function of the winged-helix protein FOXC1." in: American journal of human genetics, Vol. 68, Issue 3, pp. 627-41, (2001) (PubMed).

  • 抗原
    FOXD3 (Forkhead Box D3 (FOXD3))
    别名
    FOXD3 (FOXD3 产品)
    别名
    AIS1 antibody, Genesis antibody, HFH2 antibody, VAMAS2 antibody, CWH3 antibody, Hfh2 antibody, fkd6 antibody, fkh6 antibody, forkhead-6 antibody, zgc:111934 antibody, XFD-6 antibody, xfoxd3 antibody, FOXD3 antibody, genesis antibody, hfh2 antibody, foxd3b antibody, foxd3b-A antibody, forkhead box D3 antibody, forkhead box D3 L homeolog antibody, forkhead box D3 S homeolog antibody, FOXD3 antibody, Foxd3 antibody, foxd3 antibody, foxd3.L antibody, foxd3.S antibody
    背景

    Description: FoxD3 is a member of the Forkhead Box family and is characterized by a winged-helix DNA-binding structure and the important role it plays in embryonic development . This transcriptional regulator is required for the maintenance of pluripotency in the pre-implantation and peri-implantation stages of mouse embryonic development and is also required for trophoblast formation . FoxD3 is required for the maintenance of the mammalian neural crest, FoxD3(-/-) mouse embryos fail around the time of implantation with loss of neural crest-derived structures . FoxD3 also forms a regulatory network with Oct-4 and NANOG to maintain the pluripotency of ES cells .Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis .Tissue specificity: Expressed in chronic myeloid leukemia, Jurkat T-cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined .

    Aliases: AIS1, HFH2, Genesis, FOXD3

    分子量
    48 kDa
    基因ID
    27022
    HGNC
    27022
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