DDR1 抗体 (AA 602-681)
(2 references)Quick Overview for DDR1 抗体 (AA 602-681) (ABIN969082)
抗原
See all DDR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 602-681
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原理
- DDR1 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of DDR1 (aa602-681) expressed in E. Coli.
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亚型
- IgG1
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anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 299-330) antibody
DDR1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 568-829) antibodyDDR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 21-176) antibodyDDR1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4F2C12 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 299-330) antibodyDDR1 适用: 人 WB, IHC (p), FACS, IF 宿主: 兔 Polyclonal RB14442 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 17-47), (N-Term) antibodyDDR1 适用: 人, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB01477 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 17-47) antibodyDDR1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 21-120) antibodyDDR1 适用: 大鼠, 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) antibodyDDR1 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 4C4 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 396-430) antibodyDDR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50593 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 22-876) antibodyDDR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Discoidin domain receptor (DDR) 1 and 2: collagen-activated tyrosine kinase receptors in the cornea." in: Experimental eye research, Vol. 72, Issue 1, pp. 87-92, (2001) (PubMed).
: "Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric receptors." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 14, Issue 7, pp. 973-81, (2000) (PubMed).
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: "Discoidin domain receptor (DDR) 1 and 2: collagen-activated tyrosine kinase receptors in the cornea." in: Experimental eye research, Vol. 72, Issue 1, pp. 87-92, (2001) (PubMed).
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- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
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别名
- DDR1
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背景
- DDR1: discoidin domain receptor tyrosine kinase 1. Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. This gene is located on chromosome 6p21.3 in proximity to several HLA class I genes. Alternative splicing of this gene results in multiple transcript variants.
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UniProt
- Q08345
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途径
- RTK signaling, Smooth Muscle Cell Migration
抗原
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