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Bcl-2 抗体

BCL2 适用: 人, 小鼠 IHC, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 8E12 unconjugated
产品编号 ABIN968975
发货至: 中国
  • 抗原 See all Bcl-2 (BCL2) 抗体
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    适用
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    人, 小鼠
    宿主
    • 323
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    小鼠
    克隆类型
    • 320
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    单克隆
    标记
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    This Bcl-2 antibody is un-conjugated
    应用范围
    • 334
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    Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)
    原理
    BCL-2 Antibody
    纯化方法
    Ascitic fluid
    免疫原
    Synthetic peptide corresponding to residues surrounding BCL-2, conjugated to KLH.
    克隆位点
    8E12
    亚型
    IgG1
    Top Product
    Discover our top product BCL2 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Choi, Feng, Yoon: "FKBP38 protects Bcl-2 from caspase-dependent degradation." in: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9770-9, (2010) (PubMed).

    Munda, Hajdinjak, Kavalar, Stiblar Martincic: "p53, Bcl-2 and AgNOR tissue markers: model approach in predicting prostate cancer characteristics." in: The Journal of international medical research, Vol. 37, Issue 6, pp. 1868-76, (2010) (PubMed).

    Murphy, Green, Adams, Squire, Kuo, McKay: "Pharmacogenomics in the curricula of colleges and schools of pharmacy in the United States." in: American journal of pharmaceutical education, Vol. 74, Issue 1, pp. 7, (2010) (PubMed).

  • 抗原
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    别名
    BCL-2 (BCL2 产品)
    背景

    Description: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.Tissue specificity: Expressed in a variety of tissues.

    Aliases: Bcl-2, BCL2

    分子量
    26kDa
    基因ID
    596
    HGNC
    596
    UniProt
    P10415
    途径
    MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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