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AXL 抗体

This anti-AXL antibody is a 小鼠 单克隆 antibody detecting AXL in ELISA 和 ICC. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN968974
发货至: 中国

Quick Overview for AXL 抗体 (ABIN968974)

抗原

See all AXL 抗体
AXL (AXL Receptor tyrosine Kinase (AXL))

适用

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宿主

  • 124
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  • 1
小鼠

克隆类型

  • 122
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  • 2
单克隆

标记

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This AXL antibody is un-conjugated

应用范围

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ELISA, Immunocytochemistry (ICC)

克隆位点

7E10
  • 原理

    AXL Antibody

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant extracellular fragment of human AXL fused with hIgGFc tag expressed in HEK293 cell line.

    亚型

    IgG1
  • 应用备注

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Vajkoczy, Knyazev, Kunkel, Capelle, Behrndt, von Tengg-Kobligk, Kiessling, Eichelsbacher, Essig, Read, Erber, Ullrich: "Dominant-negative inhibition of the Axl receptor tyrosine kinase suppresses brain tumor cell growth and invasion and prolongs survival." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 15, pp. 5799-804, (2006) (PubMed).

  • 抗原

    AXL (AXL Receptor tyrosine Kinase (AXL))

    别名

    AXL

    背景

    AXL: AXL receptor tyrosine kinase, also known as UFO, JTK11. Entrez Protein NP_001690. It is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

    分子量

    97.4 kDa

    基因ID

    558

    UniProt

    P30530

    途径

    RTK signaling, Cellular Response to Molecule of Bacterial Origin
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