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PPP1R10 抗体 (AA 605-716)

PPP1R10 适用: 人, 大鼠, 小鼠 WB, IF 宿主: 小鼠 Monoclonal 47-PNUTS unconjugated
产品编号 ABIN968349
发货至: 中国
  • 抗原 See all PPP1R10 抗体
    PPP1R10 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 10 (PPP1R10))
    抗原表位
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 605-716
    适用
    • 12
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 11
    • 1
    小鼠
    克隆类型
    • 11
    • 1
    单克隆
    标记
    • 12
    This PPP1R10 antibody is un-conjugated
    应用范围
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    交叉反应
    人, 小鼠
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Rat PNUTS aa. 605-716
    克隆位点
    47-PNUTS
    亚型
    IgG1
    Top Product
    Discover our top product PPP1R10 Primary Antibody
  • 说明

    Related Products: ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20°C.
  • Allen, Kwon, Nairn, Greengard: "Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit." in: The Journal of biological chemistry, Vol. 273, Issue 7, pp. 4089-95, (1998) (PubMed).

  • 抗原
    PPP1R10 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 10 (PPP1R10))
    别名
    PNUTS (PPP1R10 产品)
    别名
    CAT53 antibody, FB19 antibody, PNUTS antibody, PP1R10 antibody, R111 antibody, p99 antibody, Fb19 antibody, Pnuts antibody, 2610025H06Rik antibody, Cat53 antibody, D17Ertd808e antibody, CHUNP6885 antibody, fe15d12 antibody, fk54b08 antibody, ppp1r10l antibody, wu:fe15d12 antibody, wu:fk54b08 antibody, protein phosphatase 1 regulatory subunit 10 antibody, protein phosphatase 1, regulatory subunit 10 antibody, protein phosphatase 1 regulatory subunit 10 S homeolog antibody, PPP1R10 antibody, Ppp1r10 antibody, ppp1r10.S antibody, ppp1r10 antibody
    背景
    Many aspects of cellular physiology are influenced by the serine/threonine protein phosphatase1 (PP1). It is a highly conserved eukaryotic protein that reverses the action of protein kinases. PP1 is key to such processes as cell division, neuronal metabolism, and protein synthesis. It consists of a catalytic subunit, with a broad substrate specificity, whose action is directed by its association with a family of regulatory proteins including inhibitor-1, inhibitor-2, and NIPP-1. In response to extracellular stimuli, these proteins interact with PP1 and inhibit its catalytic activity. Other regulatory proteins are referred to as targeting subunits because they direct PP1 to specific subcellular locations and modulate its activity. In the cell nucleus, PP1 has been implicated in a variety of processes. Nuclear PP1 exists in high MW complexes with other proteins including NIPP-1. PNUTS (phosphatase 1 nuclear targeting subunit) is a ubiquitously expressed nuclear protein that forms a stable complex with PP1 and is thought to modulate its catalytic activity. Thus, PNUTS is a specific regulatory protein that directs the nuclear function of PP1.
    分子量
    110 kDa
    途径
    Protein targeting to Nucleus
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