TEAD1 抗体 (AA 86-199)
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- 抗原 See all TEAD1 抗体
- TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))
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抗原表位
- AA 86-199
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适用
- 人, 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TEAD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 小鼠
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human TEF-1 aa. 86-199
- 克隆位点
- 31-TEF
- 亚型
- IgG1
- Top Product
- Discover our top product TEAD1 Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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Identification of the functional domain in the transcription factor RTEF-1 that mediates alpha 1-adrenergic signaling in hypertrophied cardiac myocytes." in: The Journal of biological chemistry, Vol. 275, Issue 23, pp. 17476-80, (2000) (PubMed).
: "The human transcription enhancer factor-1, TEF-1, can substitute for Drosophila scalloped during wingblade development." in: The Journal of biological chemistry, Vol. 272, Issue 16, pp. 10664-8, (1997) (PubMed).
: "Transcription enhancer factor 1 interacts with a basic helix-loop-helix zipper protein, Max, for positive regulation of cardiac alpha-myosin heavy-chain gene expression." in: Molecular and cellular biology, Vol. 17, Issue 7, pp. 3924-36, (1997) (PubMed).
: "A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain." in: The Journal of biological chemistry, Vol. 271, Issue 36, pp. 21775-85, (1996) (PubMed).
: "Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1." in: Cell, Vol. 65, Issue 4, pp. 551-68, (1991) (PubMed).
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Identification of the functional domain in the transcription factor RTEF-1 that mediates alpha 1-adrenergic signaling in hypertrophied cardiac myocytes." in: The Journal of biological chemistry, Vol. 275, Issue 23, pp. 17476-80, (2000) (PubMed).
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- 抗原
- TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))
- 别名
- TEF-1 (TEAD1 产品)
- 别名
- tead1 antibody, zgc:63696 antibody, TEAD1 antibody, xtead1 antibody, 2610024B07Rik antibody, B230114H05Rik antibody, Gtrgeo5 antibody, TEAD-1 antibody, TEF-1 antibody, Tcf13 antibody, mTEF-1 antibody, AA antibody, NTEF-1 antibody, REF1 antibody, TCF-13 antibody, TCF13 antibody, XNTEF-1 antibody, xlNTEF-1 antibody, TEA domain family member 1a antibody, TEA domain transcription factor 1 antibody, TEA domain family member 1 (SV40 transcriptional enhancer factor) antibody, TEA domain family member 1 antibody, TEA domain family member 1 (SV40 transcriptional enhancer factor) S homeolog antibody, TEA domain family member 1b antibody, tead1a antibody, TEAD1 antibody, tead1 antibody, Tead1 antibody, tead1.S antibody, tead1b antibody
- 背景
- TEF-1 (transcription enhancer factor-1) is a member of a family of transcription factors that contain an evolutionarily conserved DNA binding domain (DBD), TEA/ATTS. TEF-1 was identified as a HeLa cell transcriptional activator that bound, via its TEA domain, to the GT-IIC and Sph enhancer elements. Comparison of various enhancers indicates that TEF-1 binds to highly degenerate DNA sequences and cooperatively interacts with tandem repeats of its binding sites, which increases its enhancer activity. However, the DNA binding activities of TEF-1 are modulated by sequences outside the DBD. The N-terminal basic portion of TEF-1 contains the DBD. The C-terminal portion contains the transactivation domain and a zinc finger-like motif that is thought to be involved in protein dimerization or interaction with additional transcription factors. TEF-1 induced transcription requires a limiting transcriptional intermediary factor (TIF) and a TATA-binding protein associated factor (hTAFIIs). Although TEF-1 is expressed ubiquitously during embryogenesis, its expression is limited to adult kidney, heart, brain, skeletal muscle, and lungs. Disruption of murine TEF-1 gene results in fetal death.
- 分子量
- 53 kDa
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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