电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Golgin A2 (GOLGA2) (AA 869-982) 抗体

GOLGA2 适用: 人, 小鼠, 大鼠, 犬 WB, IHC, IF, IP 宿主: 小鼠 Monoclonal 35-GM130 unconjugated
产品编号 ABIN968197
发货至: 中国
  • 抗原 See all Golgin A2 (GOLGA2) 抗体
    Golgin A2 (GOLGA2)
    抗原表位
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 869-982
    适用
    人, 小鼠, 大鼠, 犬
    宿主
    • 33
    • 8
    小鼠
    克隆类型
    • 34
    • 7
    单克隆
    标记
    • 25
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 25
    • 14
    • 13
    • 13
    • 13
    • 10
    • 9
    • 8
    • 7
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    交叉反应
    人, 犬, 小鼠
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    免疫原
    Rat GM130 aa. 869-982
    克隆位点
    35-GM130
    亚型
    IgG1 kappa
    Top Product
    Discover our top product GOLGA2 Primary Antibody
  • 说明

    Related Products: ABIN968545, ABIN967389

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    250 μg/mL
    缓冲液
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store undiluted at -20° C.
  • Ireton, Davis, van Hengel, Mariner, Barnes, Thoreson, Anastasiadis, Matrisian, Bundy, Sealy, Gilbert, van Roy, Reynolds: "A novel role for p120 catenin in E-cadherin function." in: The Journal of cell biology, Vol. 159, Issue 3, pp. 465-76, (2002) (PubMed).

    Marra, Maffucci, Daniele, Tullio, Ikehara, Chan, Luini, Beznoussenko, Mironov, De Matteis: "The GM130 and GRASP65 Golgi proteins cycle through and define a subdomain of the intermediate compartment." in: Nature cell biology, Vol. 3, Issue 12, pp. 1101-13, (2002) (PubMed).

    Perez, Pernet-Gallay, Nizak, Goodson, Kreis, Goud: "CLIPR-59, a new trans-Golgi/TGN cytoplasmic linker protein belonging to the CLIP-170 family." in: The Journal of cell biology, Vol. 156, Issue 4, pp. 631-42, (2002) (PubMed).

    Ralston, Lu, Ploug: "The organization of the Golgi complex and microtubules in skeletal muscle is fiber type-dependent." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 24, pp. 10694-705, (2000) (PubMed).

    Nakamura, Lowe, Levine, Rabouille, Warren: "The vesicle docking protein p115 binds GM130, a cis-Golgi matrix protein, in a mitotically regulated manner." in: Cell, Vol. 89, Issue 3, pp. 445-55, (1997) (PubMed).

  • 抗原
    Golgin A2 (GOLGA2)
    别名
    GM130 (GOLGA2 产品)
    别名
    gm130 antibody, MGC81213 antibody, AW555139 antibody, GM130 antibody, mKIAA4150 antibody, Gm130 antibody, golgin A2 S homeolog antibody, golgin A2 antibody, golgi autoantigen, golgin subfamily a, 2 antibody, golga2.S antibody, GOLGA2 antibody, Golga2 antibody
    背景
    Maturation and post-translational modification of proteins occurs after their biosynthesis at the endoplasmic reticulum and their transport through the Golgi apparatus. The process involves the transport of vesicles carrying the proteins through a vectorial process of vesicle budding and fusion from the cis-compartment to the medial-compartment and the trans-compartment of the Golgi apparatus. The detergent insoluble fraction of the Golgi is named matrix and is required for proper morphology of the Golgi membranes. GM130 (Golgi matrix protein of 130 kDa) is a protein isolated from the Triton™ X-100-insoluble Golgi matrix and peripherally associated with the cis-compartment, as demonstrated by co-localization with syntaxin5. GM130 is homologous to the Golgi autoantigen golgin 95. GM130 interacts through its N-terminal domain with p115 and with the Golgi membranes at the C-terminal portion. Furthermore, the mitotic phosphorylation of GM130 blocks the interaction with p115. Thus, GM130 appears to function as a structural element of the Golgi apparatus that also provides attachment sites for membranes and other Golgi proteins. The 35/GM130 monoclonal antibody recognizes GM130, regardless of phosphorylation status.
    分子量
    130 kDa
    途径
    SARS-CoV-2 Protein Interactome
You are here:
客服