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TRADD 抗体 (AA 163-312)

Name: TRADD 抗体 (AA 163-312)
SKU: ABIN968045
Availability: OutOfStock

This anti-TRADD antibody is a 小鼠单克隆 antibody detecting TRADD in WB, IHC, IF 和 IP. Suitable for 人和大鼠. This Primary Antibody has been cited in 4+ publications.

Western blot analysis of TRADD on a Jurkat cell lysate (Human T-cell leukemia, ATCC TIB-152). (TRADD 抗体 (AA 163-312))

Immunofluorescence staining of HeLa cells (Human cervical epitheloid carcinoma, ATCC CCL-2. (TRADD 抗体 (AA 163-312))

2 images

(4 references)

产品编号 ABIN968045

发货至: 中国

Quick Overview for TRADD 抗体 (AA 163-312) (ABIN968045)

抗原

See all TRADD 抗体

TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

适用

人, 大鼠

宿主

小鼠

克隆类型

单克隆

标记

This TRADD antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

37-TRADD

Discover our top product TRADD Primary Antibody

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AA 163-312

交叉反应

大鼠

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Human TRADD aa. 163-312

亚型

IgG1
anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 1-312) antibody
TRADD 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 111-230) antibody
TRADD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) (N-Term) antibody
TRADD 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 1-177) antibody
TRADD 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3A1E8 unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) antibody
TRADD 适用: 人, 小鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 126-151) antibody
TRADD 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB18788 unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 133-159), (Middle Region) antibody
TRADD 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) (C-Term) antibody
TRADD 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 61-297) antibody
TRADD 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-TNFRSF1A-Associated Via Death Domain (TRADD) (AA 203-312) antibody
TRADD 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3G3 unconjugated

说明

Related Products: ABIN968537, ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20° C.
He, Ting: "A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells." in: Molecular and cellular biology, Vol. 22, Issue 17, pp. 6034-45, (2002) (PubMed).

Morgan, Thorburn, Pandolfi, Thorburn: "Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms." in: The Journal of cell biology, Vol. 157, Issue 6, pp. 975-84, (2002) (PubMed).

Yount, Afshar, Ries, Korn, Shalev, Basila, McCormick, Haas-Kogan: "Transcriptional activation of TRADD mediates p53-independent radiation-induced apoptosis of glioma cells." in: Oncogene, Vol. 20, Issue 22, pp. 2826-35, (2001) (PubMed).

Park, Baichwal: "Systematic mutational analysis of the death domain of the tumor necrosis factor receptor 1-associated protein TRADD." in: The Journal of biological chemistry, Vol. 271, Issue 16, pp. 9858-62, (1996) (PubMed).
抗原

TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))

别名

TRADD

背景

TNFalpha (Tumor Necrosis Factor) stimulates programmed cell death and NF-kappaB activation as a result of its binding to the TNF receptor 1 (TNFR1). Within this receptor, a sequence referred to as the death domain” has been shown to be necessary for both of these functions. Using the yeast two-hybrid system to detect proteins which interact with the receptor through this death domain”, a 34 kDa protein was found and designated TRADD (TNFR1-Associated Death Domain protein). TRADD appears to contain no intrinsic catalytic activity. It also contains a death domain and it has been shown to bind to FADD and RIP. Mutational analysis of TRADD demonstrates that programmed cell death and NF-kappaB activation are distinct and controlled independently.
Synonyms: TNFR1-Associated Death Domain protein

分子量

34 kDa

途径

NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C