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TRADD 抗体

TRADD 适用: 人, 小鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6265700
发货至: 中国
  • 抗原 See all TRADD 抗体
    TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
    适用
    • 46
    • 17
    • 13
    • 3
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    • 1
    • 1
    人, 小鼠, 猴
    宿主
    • 46
    • 3
    克隆类型
    • 46
    • 3
    多克隆
    标记
    • 28
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRADD antibody is un-conjugated
    应用范围
    • 38
    • 26
    • 25
    • 18
    • 14
    • 9
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    TRADD antibody detects endogenous levels of total TRADD
    交叉反应
    人, 猴, 小鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human TRADD
    亚型
    IgG
    Top Product
    Discover our top product TRADD Primary Antibody
  • 应用备注
    WB: 1:500~1:3000 IHC: 1:50~1:200, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
    别名
    TRADD (TRADD 产品)
    别名
    TRADD antibody, Hs.89862 antibody, 9130005N23Rik antibody, AA930854 antibody, wu:fc59e02 antibody, zgc:103556 antibody, tradd antibody, TNFRSF1A associated via death domain antibody, conjugal transfer protein D antibody, TNFRSF1A-associated via death domain antibody, TNFRSF1A-associated via death domain L homeolog antibody, tnfrsf1a-associated via death domain antibody, TRADD antibody, traDd antibody, Tradd antibody, tradd.L antibody, tradd antibody
    背景

    Description: The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.

    Gene: TRADD

    分子量
    34kDa
    基因ID
    8717
    UniProt
    Q15628
    途径
    NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C
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