Flotillin 2 抗体 (AA 122-379)
(5 references)Quick Overview for Flotillin 2 抗体 (AA 122-379) (ABIN967932)
抗原
See all Flotillin 2 (FLOT2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 122-379
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交叉反应
- 犬, 大鼠, 小鼠, 小鸡
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产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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免疫原
- Human ESA aa. 122-379
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亚型
- IgG1
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anti-Flotillin 2 (FLOT2) (C-Term) antibody
FLOT2 适用: 人 WB, IHC (p), IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Flotillin 2 (FLOT2) (AA 1-379) antibodyFLOT2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3G6 unconjugated
anti-Flotillin 2 (FLOT2) (AA 1-379) antibodyFLOT2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Flotillin 2 (FLOT2) (AA 169-344) antibodyFLOT2 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC, IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-Flotillin 2 (FLOT2) (AA 239-428) antibodyFLOT2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Flotillin 2 (FLOT2) (C-Term) antibodyVerified FLOT2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Flotillin 2 (FLOT2) (AA 1-379) antibodyFLOT2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Flotillin 2 (FLOT2) antibodyFLOT2 适用: 化学剂 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Flotillin 2 (FLOT2) antibodyFLOT2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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说明
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Related Products: ABIN968536, ABIN967389
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 250 μg/mL
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缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store undiluted at -20° C.
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: "Proteomic analysis of a detergent-resistant membrane skeleton from neutrophil plasma membranes." in: The Journal of biological chemistry, Vol. 277, Issue 45, pp. 43399-409, (2002) (PubMed).
: "Ca(++)-dependent vesicle release from erythrocytes involves stomatin-specific lipid rafts, synexin (annexin VII), and sorcin." in: Blood, Vol. 99, Issue 7, pp. 2569-77, (2002) (PubMed).
: "Differential targeting of beta -adrenergic receptor subtypes and adenylyl cyclase to cardiomyocyte caveolae. A mechanism to functionally regulate the cAMP signaling pathway." in: The Journal of biological chemistry, Vol. 275, Issue 52, pp. 41447-57, (2001) (PubMed).
: "Glycosylphosphatidyl inositol-anchored proteins and fyn kinase assemble in noncaveolar plasma membrane microdomains defined by reggie-1 and -2." in: Molecular biology of the cell, Vol. 12, Issue 10, pp. 3031-45, (2001) (PubMed).
: "Cloning and characterization of a novel epidermal cell surface antigen (ESA)." in: The Journal of biological chemistry, Vol. 269, Issue 31, pp. 19983-91, (1994) (PubMed).
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: "Proteomic analysis of a detergent-resistant membrane skeleton from neutrophil plasma membranes." in: The Journal of biological chemistry, Vol. 277, Issue 45, pp. 43399-409, (2002) (PubMed).
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- Flotillin 2 (FLOT2)
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别名
- Flotillin-2
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背景
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Flotillin-2/ESA (epidermal surface antigen) plays a role in intercellular epidermal adhesion. Epidermal surface proteins have an important role in normal epidermal maintenance and function. In addition, they are involved in various autoimmune diseases in which auto-antibodies bind to normal epidermal cell surface proteins. This binding causes cell disadherence that leads to blister formation. Such antibodies have been utilized to identify new proteins involved in epidermal cell adhesion. One of these antibodies, ECS-1, was used to isolate Flotillin-2/ESA. The single copy ESA gene is located on the long arm of human chromosome 17, in the region containing the gene for neurofibromatosis 1 (NF1). ESA mRNA is expressed in cultured keratinocytes, melanocytes, fibroblasts, and carcinoma and melanoma cell lines. Flotillin-2/ESA may play a critical role in epidermal structure and maintenance.
Synonyms: ESA -
分子量
- 42 kDa
抗原
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