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FAS 抗体 (AA 1-163)

Name: FAS 抗体 (AA 1-163)
SKU: ABIN967816
Availability: OutOfStock

This anti-FAS antibody is a 小鼠单克隆 antibody detecting FAS in WB, IP, IF 和 IHC (f). Suitable for 人, 大鼠, 小鼠, 犬和小鸡. This Primary Antibody has been cited in 4+ publications.

Western blot analysis of CD95 on a Daudi cell lysate (Human B lymphoblast, ATCC CCL-213). (FAS 抗体 (AA 1-163))

Immunohistochemical staining of a formalin-fixed rabbit liver section. (FAS 抗体 (AA 1-163))

IHC

2 images

(4 references)

产品编号 ABIN967816

发货至: 中国

Datasheet as PDF

Quick Overview for FAS 抗体 (AA 1-163) (ABIN967816)

抗原

See all FAS 抗体

FAS (TNF Receptor Superfamily, Member 6 (FAS))

适用

人, 大鼠, 小鼠, 犬, 小鸡

宿主

小鼠

克隆类型

单克隆

标记

This FAS antibody is un-conjugated

应用范围

Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

13-Fas

Discover our top product FAS Primary Antibody

抗原表位
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16

16

8

8

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6

6

6

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5

4

4

4

4

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2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-163

交叉反应

小鸡, 犬, 小鼠, 大鼠

产品特性

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

纯化方法

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

免疫原

Human Fas aa. 1-163

亚型

IgG2a kappa
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 150-250) antibody
FAS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) antibody
FAS 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 4F8H6 unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 87-109), (N-Term) antibody
FAS 适用: 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 22-172) antibody
FAS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 22-169) antibody
FAS 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 21-170) antibody
FAS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibody
FAS 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2G3 unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibody
FAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 5B4 unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 1-335) antibody
FAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1B6 unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 26-96) antibody
FAS 适用: 人 FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal FAS-3112 unconjugated

说明

Related Products: ABIN967389

限制

仅限研究用
状态

Liquid

浓度

250 μg/mL

缓冲液

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store undiluted at -20°C.
Rosen, Coll, Li, Filmus: "Transforming growth factor-alpha prevents detachment-induced inhibition of c-Src kinase activity, Bcl-XL down-regulation, and apoptosis of intestinal epithelial cells." in: The Journal of biological chemistry, Vol. 276, Issue 40, pp. 37273-9, (2001) (PubMed).

Zhuang, Demirs, Kochevar: "Protein kinase C inhibits singlet oxygen-induced apoptosis by decreasing caspase-8 activation." in: Oncogene, Vol. 20, Issue 46, pp. 6764-76, (2001) (PubMed).

MacLaren, Clark, Gillespie: "v-Jun sensitizes cells to apoptosis by a mechanism involving mitochondrial cytochrome C release." in: Oncogene, Vol. 19, Issue 51, pp. 5906-18, (2000) (PubMed).

Arnold, Seifert, Asadullah, Volk: "Crosstalk between keratinocytes and T lymphocytes via Fas/Fas ligand interaction: modulation by cytokines." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 12, pp. 7140-7, (1999) (PubMed).
抗原

FAS (TNF Receptor Superfamily, Member 6 (FAS))

别名

CD95

背景

CD95 is a member of a family of cell surface receptors that includes tumor necrosis factor receptor (TNF-R), nerve growth factor receptor (NGF-R), CD40, CD27, CD30, and 4-1BB. Both murine and human Fas genes have been cloned and reportedly share 60% similarity in their amino acid sequences. CD95 (Fas) is a cell surface apoptosis-signaling molecule that is widely expressed in sites such as thymus, liver, heart, and ovary. Abnormalities in the Fas gene correlate with autoimmune features in mice and with unusually high levels of lymphocyte apoptosis in HIV-infected humans. Genetic studies have localized the Fas gene near the lpr (lymphoproliferation disease) locus on mouse chromosome 19 and further characterization reportedly has revealed that lpr is a mutation affecting the function of the Fas gene. This antibody is routinely tested by western blot analysis.
Synonyms: Fas, APO-1

分子量

45 kDa

途径

p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity