HNRNPU 抗体 (AA 326-632)
(5 references)-
- 抗原 See all HNRNPU 抗体
- HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))
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抗原表位
- AA 326-632
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适用
- 人, 小鼠, 大鼠, 犬, 小鸡
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HNRNPU antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
- 交叉反应
- 人, 大鼠, 小鸡, 犬
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Mouse pp120 aa. 326-632
- 克隆位点
- 98-pp120
- 亚型
- IgG1
- Top Product
- Discover our top product HNRNPU Primary Antibody
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anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) antibody
HNRNPU 适用: 人 WB, IHC, IP, IF 宿主: 兔 Monoclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) (AA 608-825) antibodyHNRNPU 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) antibodyHNRNPU 适用: 人, 小鼠, 猴 WB, ELISA, IP, IF, IHC (p), FACS, ICC 宿主: 小鼠 Monoclonal 3G6 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) (AA 352-460) antibodyHNRNPU 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G11 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) (AA 1-40) antibodyHNRNPU 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) (N-Term) antibodyHNRNPU 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) (AA 766-800), (C-Term) antibodyHNRNPU 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51596 unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) antibodyHNRNPU 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) (AA 651-700) antibodyHNRNPU 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, Pig, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) (AA 110-159) antibodyHNRNPU 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, Pig, 猴, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968533, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20° C.
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: "VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam." in: Molecular biology of the cell, Vol. 13, Issue 4, pp. 1175-89, (2002) (PubMed).
: "The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF." in: The Journal of biological chemistry, Vol. 277, Issue 15, pp. 12906-14, (2002) (PubMed).
: "Epithelial mesenchymal transition by c-Fos estrogen receptor activation involves nuclear translocation of beta-catenin and upregulation of beta-catenin/lymphoid enhancer binding factor-1 transcriptional activity." in: The Journal of cell biology, Vol. 148, Issue 1, pp. 173-88, (2000) (PubMed).
: "p120 catenin regulates the actin cytoskeleton via Rho family GTPases." in: The Journal of cell biology, Vol. 150, Issue 3, pp. 567-80, (2000) (PubMed).
: "Adhesion and signaling proteins spatiotemporally associated with spermiation in the rat." in: Journal of andrology, Vol. 20, Issue 2, pp. 198-213, (1999) (PubMed).
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: "VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam." in: Molecular biology of the cell, Vol. 13, Issue 4, pp. 1175-89, (2002) (PubMed).
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- 抗原
- HNRNPU (Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU))
- 别名
- pp120 (HNRNPU 产品)
- 别名
- AA408410 antibody, AI256620 antibody, AL024194 antibody, AL024437 antibody, AW557595 antibody, C86794 antibody, Hnrpu antibody, SAFA antibody, Sp120 antibody, hnRNP U antibody, SN1 antibody, HNRPU antibody, SAF-A antibody, U21.1 antibody, saf-a antibody, heterogeneous nuclear ribonucleoprotein U antibody, heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) S homeolog antibody, heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) antibody, Hnrnpu antibody, HNRNPU antibody, hnrnpu.S antibody
- 背景
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The membrane associated protein p120 Catenin (pp120 (Src substrate), p120cas) was identified as a tyrosine kinase substrate that is phosphorylated in Src transformed cells or in response to growth factor stimulation. It shares structural similarity with the Drosophila Armadillo protein and the vertebrate beta-catenin and gamma-catenin proteins. This similarity is evidenced by its characteristic Arm domain that is composed of 42-amino acid motif repeats. In the cell, p120 Catenin is localized to the E-Cadherin/catenins cell adhesion complex. Like beta- and gamma-catenin, p120 Catenin directly associates with the cytoplasmic C-terminus of E-Cadherin via its Arm domain and may similarly interact with other Cadherins. It exists as four isoforms that range in size from 90-115 kDa. Expression of these isoforms is heterogeneous in human carcinomas, suggesting that altered pp120 expression contributes to malignancy due to loss of functional cell adhesions. Multiple tyrosine residues (Y96, Y112, Y228, Y280, Y257, Y291, Y296, and Y302) in p120 Catenin are phosphorylated by Src and these phosphorylations may facilitate interaction with PTP1C/SHP-1 in response to EGF stimulation. Thus, p120 Catenin is an Arm domain protein that interacts with both cell adhesion molecules, such as cadherins and cell signaling molecules, such as PTP1C.
Synonyms: pp120 (Src Substrate), p120cas - 分子量
- 120 kDa
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