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IGF1R 抗体

IGF1R 适用: 人 FACS, FM 宿主: 小鼠 Monoclonal 1H7 unconjugated
产品编号 ABIN967487
发货至: 中国
  • 抗原 See all IGF1R 抗体
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    适用
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    宿主
    • 176
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    小鼠
    克隆类型
    • 178
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    单克隆
    标记
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    This IGF1R antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Fluorescence Microscopy (FM)
    品牌
    BD Pharmingen™
    产品特性
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    纯化方法
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    克隆位点
    1H7
    亚型
    IgG1 kappa
    Top Product
    Discover our top product IGF1R Primary Antibody
  • 应用备注
    This product is routinely tested on peripheral blood granulocytes. The histogram is an example of the expected reactivity.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 4° C.
  • Kooijman, Scholtens, Rijkers, Zegers: "Differential expression of type I insulin-like growth factor receptors in different stages of human T cells." in: European journal of immunology, Vol. 25, Issue 4, pp. 931-5, (1995) (PubMed).

    Li, Kato, Paz, Kasuya, Fujita-Yamaguchi: "Two new monoclonal antibodies against the alpha subunit of the human insulin-like growth factor-I receptor." in: Biochemical and biophysical research communications, Vol. 196, Issue 1, pp. 92-8, (1993) (PubMed).

    Xiong, Kasuya, Li, Kato, Fujita-Yamaguchi: "Growth-stimulatory monoclonal antibodies against human insulin-like growth factor I receptor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 12, pp. 5356-60, (1992) (PubMed).

  • 抗原
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    别名
    CD221 (IGF1R 产品)
    别名
    CMT2N antibody, CD221 antibody, IGFIR antibody, IGFR antibody, JTK13 antibody, IGFIRC antibody, IGFR1 antibody, IGF-1R antibody, IGF1R antibody, DKFZp469I0618 antibody, igf-1r antibody, xIGF-1R antibody, xIGFR antibody, xigf1r antibody, A330103N21Rik antibody, D930020L01 antibody, hyft antibody, igf-ir antibody, IGF-IR antibody, IGF-IRb antibody, wu:fb03h06 antibody, IGF-IRa antibody, sb:eu1090 antibody, wu:fi20b10 antibody, alanyl-tRNA synthetase antibody, insulin like growth factor 1 receptor antibody, insulin-like growth factor 1 receptor antibody, insulin-like growth factor 1 antibody, insulin-like growth factor I receptor antibody, insulin like growth factor 1 receptor S homeolog antibody, insulin-like growth factor 1b receptor antibody, insulin-like growth factor 1a receptor antibody, AARS antibody, IGF1R antibody, Igf1r antibody, igf1r antibody, Igf1 antibody, LOC780503 antibody, LOC100136427 antibody, igf1r.S antibody, igf1rb antibody, igf1ra antibody
    背景
    Reacts with human insulin-like growth factor-I (IGF-I) receptor alpha subunit (135 kDa). IGF-IRalpha is a glycoprotein complex composed of two extracellular alpha subunits and two transmembrane beta subunits. The transmembrane subunits play a role in tyrosine phosphorylation of several intracellular signaling proteins. IGF-IRalpha is structurally and functionally similar to insulin receptor and is expressed on a variety of human hematopoietic and non-hematopoietic cells. It mediates the effects of IGF-I and IGF-II on cellular growth. 1H7 does not cross react with human insulin receptor and it can block IGF-I or IGF-II stimulated cell growth. This antibody is routinely tested by flow cytometric analysis.
    Synonyms: IGF-I Receptor alpha
    途径
    RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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