PCNA 抗体 (C-Term, ubLys164)
Quick Overview for PCNA 抗体 (C-Term, ubLys164) (ABIN966812)
抗原
See all PCNA 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- C-Term, ubLys164
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                                            免疫原
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                        Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-residues of human PCNA (proliferating cell nuclear antigen)
 Note: Antigen containing K164 amino group with the ubiquitin c-terminal 7-mer peptide bound: CLRLRGG
 
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                                            限制
- 仅限研究用
 
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                                            储存条件
- 4 °C
 
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                                            : "Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array."    in: British journal of cancer, Vol. 101, Issue 2, pp. 357-62, (2009)         (PubMed).        
 : "Stimulation index for PCNA mRNA in peripheral blood as immune function monitoring after renal transplantation." in: Transplantation, Vol. 87, Issue 9, pp. 1411-4, (2009) (PubMed).
 : "Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk." in: Carcinogenesis, Vol. 30, Issue 5, pp. 763-8, (2009) (PubMed).
 : "Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project. ..." in: Cancer research, Vol. 69, Issue 7, pp. 2956-65, (2009) (PubMed).
 : "Sequence and expression in Escherichia coli of the 40-kDa subunit of activator 1 (replication factor C) of HeLa cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 7, pp. 2516-20, (1992) (PubMed).
 : "Localization of the gene for human proliferating nuclear antigen/cyclin by in situ hybridization." in: Human genetics, Vol. 86, Issue 1, pp. 84-6, (1991) (PubMed).
 
 
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                                            : "Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array."    in: British journal of cancer, Vol. 101, Issue 2, pp. 357-62, (2009)         (PubMed).        
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    - PCNA (Proliferating Cell Nuclear Antigen (PCNA))
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                                            别名
- PCNA
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                                            背景
- The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.
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                                            途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
 抗原
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