电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

PCNA 抗体 (C-Term, ubLys164)

Cited in 6+ publications. This 兔 多克隆 anti-PCNA antibody specifically detects PCNA in IHC. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN966812
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for PCNA 抗体 (C-Term, ubLys164) (ABIN966812)

抗原

See all PCNA 抗体
PCNA (Proliferating Cell Nuclear Antigen (PCNA))

适用

  • 243
  • 176
  • 175
  • 56
  • 30
  • 29
  • 28
  • 28
  • 21
  • 20
  • 18
  • 18
  • 11
  • 11
  • 6
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 大鼠

宿主

  • 143
  • 114
  • 3

克隆类型

  • 133
  • 126
  • 1
多克隆

标记

  • 121
  • 18
  • 13
  • 8
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This PCNA antibody is un-conjugated

应用范围

  • 217
  • 82
  • 77
  • 70
  • 63
  • 59
  • 45
  • 43
  • 40
  • 33
  • 15
  • 14
  • 11
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC)
  • 抗原表位

    • 16
    • 16
    • 16
    • 16
    • 15
    • 11
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term, ubLys164

    免疫原

    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-residues of human PCNA (proliferating cell nuclear antigen)
    Note: Antigen containing K164 amino group with the ubiquitin c-terminal 7-mer peptide bound: CLRLRGG
  • 限制

    仅限研究用
  • 储存条件

    4 °C
  • Kweekel, Antonini, Nortier, Punt, Gelderblom, Guchelaar: "Explorative study to identify novel candidate genes related to oxaliplatin efficacy and toxicity using a DNA repair array." in: British journal of cancer, Vol. 101, Issue 2, pp. 357-62, (2009) (PubMed).

    Niwa, Miwa, Kuzuya, Iwasaki, Haneda, Ueki, Katayama, Hiramitsu, Goto, Nagasaka, Watarai, Uchida, Nakao, Kobayashi: "Stimulation index for PCNA mRNA in peripheral blood as immune function monitoring after renal transplantation." in: Transplantation, Vol. 87, Issue 9, pp. 1411-4, (2009) (PubMed).

    Michiels, Laplanche, Boulet, Dessen, Guillonneau, Méjean, Desgrandchamps, Lathrop, Sarasin, Benhamou: "Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk." in: Carcinogenesis, Vol. 30, Issue 5, pp. 763-8, (2009) (PubMed).

    Canova, Hashibe, Simonato, Nelis, Metspalu, Lagiou, Trichopoulos, Ahrens, Pigeot, Merletti, Richiardi, Talamini, Barzan, Macfarlane, Macfarlane, Holcátová, Bencko, Benhamou, Bouchardy, Kjaerheim et al.: "Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project. ..." in: Cancer research, Vol. 69, Issue 7, pp. 2956-65, (2009) (PubMed).

    Chen, Pan, Hurwitz: "Sequence and expression in Escherichia coli of the 40-kDa subunit of activator 1 (replication factor C) of HeLa cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 7, pp. 2516-20, (1992) (PubMed).

    Webb, Parsons, Chenevix-Trench: "Localization of the gene for human proliferating nuclear antigen/cyclin by in situ hybridization." in: Human genetics, Vol. 86, Issue 1, pp. 84-6, (1991) (PubMed).

  • 抗原

    PCNA (Proliferating Cell Nuclear Antigen (PCNA))

    别名

    PCNA

    背景

    The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

    途径

    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
You are here: