(4 references)-
- 抗原 See all KCNH1 抗体
- KCNH1 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1 (KCNH1))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNH1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human KCNH1(Potassium voltage-gated channel subfamily H member 1)
- Top Product
- Discover our top product KCNH1 Primary Antibody
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anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1 (KCNH1) (AA 787-820) antibody
KCNH1 适用: 人 WB, FACS, IF 宿主: 兔 Polyclonal RB57957 unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1 (KCNH1) (AA 890-988) antibodyKCNH1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1 (KCNH1) antibodyKCNH1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1 (KCNH1) (Internal Region) antibodyKCNH1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1 (KCNH1) (AA 840-989) antibodyKCNH1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1 (KCNH1) (Internal Region) antibodyKCNH1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1 (KCNH1) (C-Term) antibodyKCNH1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1 (KCNH1) (AA 813-962) antibodyKCNH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1 (KCNH1) (AA 802-817), (C-Term), (Intracellular) antibodyKCNH1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 储存条件
- 4 °C
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: "Functional distinction of human EAG1 and EAG2 potassium channels." in: FEBS letters, Vol. 514, Issue 2-3, pp. 204-8, (2002) (PubMed).
: "Inhibition of human ether à go-go potassium channels by Ca(2+)/calmodulin." in: The EMBO journal, Vol. 19, Issue 13, pp. 3263-71, (2000) (PubMed).
: "Oncogenic potential of EAG K(+) channels." in: The EMBO journal, Vol. 18, Issue 20, pp. 5540-7, (1999) (PubMed).
: "Cloning of a human ether-a-go-go potassium channel expressed in myoblasts at the onset of fusion." in: FEBS letters, Vol. 434, Issue 1-2, pp. 177-82, (1998) (PubMed).
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: "Functional distinction of human EAG1 and EAG2 potassium channels." in: FEBS letters, Vol. 514, Issue 2-3, pp. 204-8, (2002) (PubMed).
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- 抗原
- KCNH1 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 1 (KCNH1))
- 别名
- KCNH1 (KCNH1 产品)
- 别名
- EAG antibody, bEAG antibody, EAG1 antibody, Kv10.1 antibody, h-eag antibody, M-eag antibody, Eag1 antibody, kcnh1 antibody, potassium voltage-gated channel subfamily H member 1 antibody, potassium channel, voltage gated eag related subfamily H, member 1 antibody, potassium voltage-gated channel, subfamily H (eag-related), member 1 antibody, potassium voltage-gated channel, subfamily H (eag-related), member 1a antibody, KCNH1 antibody, LOC490277 antibody, Kcnh1 antibody, kcnh1a antibody
- 背景
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KCNH1 (Potassium voltage-gated channel subfamily H member 1) Is a pore-forming (alpha) subunit of voltage-gated non-inactivating delayed rectifier potassium channel. Channel properties may be modulated by cAMP and subunit assembly. KCNH1 mediates IK(NI) current in myoblasts. The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. Heteromultimer with KCNH5/EAG2. KCNH1 interacts with ALG10B. KCNH1 is highly expressed in brain and in myoblasts at the onset of fusion, but not in other tissues. Detected in HeLa (cervical carcinoma), SH-SY5Y (neuroblastoma) and MCF-7 (epithelial tumor) cells, but not in normal epithelial cells. Overexpression of EAG may confer a growth advantage to cancer cells and favor tumor cell proliferation.
Synonyms: EAG (Voltage-gated potassium channel subunit Kv10.1), EAG1 (Ether-a-go-go potassium channel 1)
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