ITK 抗体 (AA 2-110)
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北京 101111
Quick Overview for ITK 抗体 (AA 2-110) (ABIN966422)
抗原
See all ITK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 2-110
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of ITK (aa2-110) expressed in E. Coli.
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亚型
- IgG1
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应用备注
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
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状态
- Liquid
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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: "Association of atopy and eczema with polymorphisms in T-cell immunoglobulin domain and mucin domain-IL-2-inducible T-cell kinase gene cluster in chromosome 5 q 33." in: The Journal of allergy and clinical immunology, Vol. 116, Issue 3, pp. 650-6, (2005) (PubMed).
: "Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch1alpha)." in: International immunology, Vol. 13, Issue 10, pp. 1265-74, (2001) (PubMed).
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- ITK (IL2-Inducible T-Cell Kinase (ITK))
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别名
- ITK
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背景
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ITK: IL2-inducible T-cell kinase. This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.
Synonyms: EMT, LYK, PSCTK2 -
基因ID
- 3702
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
抗原
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