IGF1 抗体 (AA 80-96)
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Quick Overview for IGF1 抗体 (AA 80-96) (ABIN966342)
抗原
See all IGF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 80-96
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免疫原
- A synthetic peptide corresponding to a sequence at the middle region of human IGF-1 (80-96 aa), different from the mouse and rat sequence by one amino acid.
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应用备注
- WB: The detection limit for IGF-1 is approximately 2.5ng/lane under non-reducing and reducing conditions.
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限制
- 仅限研究用
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溶解方式
- 0.2ml of distilled water will yield a concentration of 500µg/ml.
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缓冲液
- Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
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储存液
- Thimerosal (Merthiolate), Sodium azide
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储存条件
- -20 °C
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- IGF1 (Insulin-Like Growth Factor 1 (IGF1))
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别名
- IGF-1
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背景
- Insulin-like growth factor 1 (IGF-1) also known as somatomedin C or mechano growth factor is a protein that in humans is encoded by the IGF1 gene. IGF-1 is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin is used for the treatment of growth failure. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7649 daltons.Justice et al. (1990) placed the mouse IGF1 gene on chromosome 10.
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途径
- RTK signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation
抗原
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