CD14 抗体
Quick Overview for CD14 抗体 (ABIN965766)
抗原
See all CD14 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Ni-NTA purified recombinant human CD14 expressed in E. Coli strain BL21 (DE3).
-
纯化方法
- Antibodies are purified by protein G affinity chromatography.
-
亚型
- IgG1
-
-
-
-
应用备注
-
IHC: Dilution 1:200-1:400
ELISA: Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.2%BSA
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
-
- CD14
-
别名
- CD14
-
背景
- CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages.
-
基因ID
- 929
-
途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
-