Caspase 1 抗体 (N-Term)
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Quick Overview for Caspase 1 抗体 (N-Term) (ABIN965750)
抗原
See all Caspase 1 (CASP1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Purified by antigen-specific affinity chromatography.
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免疫原
- Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of fall armyworm (Spodoptera frugiperda) CASP1(Caspase-1 protein)
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应用备注
- ELISA, Western blotting: 1µg/ml for 2hrs.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- This antibody is stored in PBS, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- Caspase 1 (CASP1)
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别名
- CASP1
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背景
- CASP1(Caspase-1) is involved in the activation cascade of caspases responsible for apoptosis execution. The Caspase-1 is inhibited by the baculovirus anti-apoptotic protein p35. It cleaves p35 and nuclear immunophilin FKBP46. Caspase-1 contains a heterodimer of a 19/18 kDa (p19/18) and a 12 kDa (p12) subunit. The two subunits are derived from the precursor sequence by an autocatalytic mechanism. Caspase-1 belongs to the peptidase C14 family.
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途径
- Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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