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- 抗原 See all Cathelicidin (CAMP) 抗体
- Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))
- 适用
- 请咨询
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Cathelicidin antibody is un-conjugated
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应用范围
- ELISA
- 纯化方法
- Ascitic fluid
- 免疫原
- cAMP, conjugated to KLH.
- 克隆位点
- 9H4C4
- 亚型
- IgG1
- Top Product
- Discover our top product CAMP Primary Antibody
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- 应用备注
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ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 状态
- Liquid
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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[SOFMER, its topicality and its prospects]." in: Annales de réadaptation et de médecine physique : revue scientifique de la Société française de rééducation fonctionnelle de réadaptation et de médecine physique, Vol. 51, Issue 5, pp. 329-31, (2008) (PubMed).
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[SOFMER, its topicality and its prospects]." in: Annales de réadaptation et de médecine physique : revue scientifique de la Société française de rééducation fonctionnelle de réadaptation et de médecine physique, Vol. 51, Issue 5, pp. 329-31, (2008) (PubMed).
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- 抗原
- Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))
- 别名
- cAMP (CAMP 产品)
- 别名
- CAP-18 antibody, CAP18 antibody, CRAMP antibody, FALL-39 antibody, FALL39 antibody, LL37 antibody, CATH-2 antibody, Cnlp antibody, Cramp antibody, MCLP antibody, CATH-B1 antibody, CATHB1 antibody, CATHL2 antibody, CATHL7 antibody, CAP11 antibody, cathelicidin antimicrobial peptide antibody, CAMP antibody, LOC100136187 antibody, LOC100136439 antibody, Camp antibody
- 物质类
- Chemical
- 背景
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Cyclic adenosine monophosphate (cAMP) plays a key role as an intracellular second messenger for transduction events that follow a number of extracellular signals. The G-Protein Coupled Receptors (GPCR) is the largest family of cell surface receptors. They can be activated by different ligands, such as neurotransmitters, hormones, ions, small molecules, peptides, and other physiological signaling molecules. Typically, the binding of the ligands to its receptor resulting in the activation of G-proteins, in return, activates the effector adenylyl cyclase evoking the production of cAMP. The activation of a protein kinase by cAMP results in the phosphorylation of substrate proteins. Currently successful drugs in marketing have been developed to target these receptors. Among the GPCRs, ~367 receptors are potential drug development targets, but only about 20 have been used to generate therapeutically and commercially successful drugs so far. Because the involvement of cAMP can amplify the response of the ligand binding, the second messenger cAMP has been largely employed to monitor the activation of the GPCR to facilitate the therapeutic drug discovery
Synonyms: cAMP - 途径
- Cellular Response to Molecule of Bacterial Origin
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