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AXL 抗体 (AA 466-530)

This 小鼠 单克隆 antibody specifically detects AXL in WB 和 ELISA. It exhibits reactivity toward 人. It has been mentioned in 3+ publications
产品编号 ABIN965629
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for AXL 抗体 (AA 466-530) (ABIN965629)

抗原

See all AXL 抗体
AXL (AXL Receptor tyrosine Kinase (AXL))

适用

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宿主

  • 126
  • 24
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小鼠

克隆类型

  • 122
  • 39
  • 2
单克隆

标记

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This AXL antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

1B3A2
  • 抗原表位

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    AA 466-530

    纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of AXL(aa466-530) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.

    限制

    仅限研究用
  • 状态

    Liquid

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Collett, Sage, Kirton, Alexander, Gilmore, Canfield: "Axl/phosphatidylinositol 3-kinase signaling inhibits mineral deposition by vascular smooth muscle cells." in: Circulation research, Vol. 100, Issue 4, pp. 502-9, (2007) (PubMed).

    Rual, Venkatesan, Hao, Hirozane-Kishikawa, Dricot, Li, Berriz, Gibbons, Dreze, Ayivi-Guedehoussou, Klitgord, Simon, Boxem, Milstein, Rosenberg, Goldberg, Zhang, Wong, Franklin, Li, Albala, Lim et al.: "Towards a proteome-scale map of the human protein-protein interaction network. ..." in: Nature, Vol. 437, Issue 7062, pp. 1173-8, (2005) (PubMed).

    Budagian, Bulanova, Orinska, Duitman, Brandt, Ludwig, Hartmann, Lemke, Saftig, Bulfone-Paus: "Soluble Axl is generated by ADAM10-dependent cleavage and associates with Gas6 in mouse serum." in: Molecular and cellular biology, Vol. 25, Issue 21, pp. 9324-39, (2005) (PubMed).

  • 抗原

    AXL (AXL Receptor tyrosine Kinase (AXL))

    别名

    AXL

    背景

    AXL receptor tyrosine kinase. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Synonyms: UFO, JTK11

    基因ID

    558

    途径

    RTK signaling, Cellular Response to Molecule of Bacterial Origin
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