(2 references)-
- 抗原 See all ATP2C1 抗体
- ATP2C1 (ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1))
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适用
- 人, 猴
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ATP2C1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of ATP2C1 expressed in E. Coli.
- 克隆位点
- 4G12
- 亚型
- IgG1
- Top Product
- Discover our top product ATP2C1 Primary Antibody
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anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) (AA 119-269) antibody
ATP2C1 适用: 人 ELISA, WB, IF, IP, RNAi 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) (AA 400-660) antibodyATP2C1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) antibodyATP2C1 适用: 人, 猴 ELISA, WB, IHC 宿主: 小鼠 Monoclonal 4G12 unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) antibodyATP2C1 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) (AA 1-919) antibodyATP2C1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) (AA 1-919) antibodyATP2C1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) (AA 491-605) antibodyATP2C1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) antibodyATP2C1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) (C-Term) antibodyATP2C1 适用: 人, 小鼠, 大鼠, 猴, Cow, 兔, 犬, 豚鼠, 马, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1) (Internal Region) antibodyATP2C1 适用: 人, Cow WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 状态
- Liquid
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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: "Hailey-Hailey disease with affective disorder: report of a case with novel ATP2C1 gene mutation." in: Journal of dermatological science, Vol. 43, Issue 2, pp. 150-1, (2006) (PubMed).
: "ATP2C1 gene mutation analysis in Italian patients with Hailey-Hailey disease." in: The Journal of investigative dermatology, Vol. 125, Issue 5, pp. 933-5, (2005) (PubMed).
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: "Hailey-Hailey disease with affective disorder: report of a case with novel ATP2C1 gene mutation." in: Journal of dermatological science, Vol. 43, Issue 2, pp. 150-1, (2006) (PubMed).
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- 抗原
- ATP2C1 (ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1))
- 别名
- ATP2C1 (ATP2C1 产品)
- 别名
- ATP2C1 antibody, ATP2C1A antibody, BCPM antibody, HHD antibody, PMR1 antibody, SPCA1 antibody, hSPCA1 antibody, Spca1 antibody, si:dkey-11p23.6 antibody, SPCA antibody, 1700121J11Rik antibody, AW061228 antibody, D930003G21Rik antibody, pmr1 antibody, ATPase secretory pathway Ca2+ transporting 1 antibody, ATPase, Ca++ transporting, type 2C, member 1 antibody, ATPase, Ca++-sequestering antibody, ATP2C1 antibody, atp2c1 antibody, Atp2c1 antibody
- 背景
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ATP2C1, also known as PMR1, it belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium. The human homologue, ATP2C1 (also designated SPLA in rat), also regulates the transport of calcium in the Golgi complex and is related to other P-type ATPases family members, such as the sarco(endo)plasmic calcium ATPase (SERCA) and the plasma membrane calcium ATPase (PCMA). ATP2C1 is a transmembrane protein that exists as two splice variants, which vary by 20 amino acids. Defects in ATP2C1 cause Hailey-Hailey disease, which is an autosomal dominant disorder that is characterized by blisters and erosions of the skin. These findings provide further evidence that PMR1 plays a key role in maintaining the integrity of the epidermis by controlling intracellular calcium signaling.
Synonyms: HHD, BCPM, PMR1, SPCA1 - 分子量
- 100kDa
- 基因ID
- 27032
- 途径
- Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
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