AKT2 抗体
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北京 101111
Quick Overview for AKT2 抗体 (ABIN965531)
抗原
See all AKT2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Akt2 (Ab-474) antibody detects endogenous levels of total Akt2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human Akt2 around the phosphorylation site of serine 474 (Q-F-SP-Y-S).
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应用备注
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WB: 1:500~1:1000
IHC: 1:50~1:100. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100ug/100ul.
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K." in: Cancer research, Vol. 61, Issue 16, pp. 5985-91, (2001) (PubMed).
: "Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer." in: Oncogene, Vol. 19, Issue 19, pp. 2324-30, (2000) (PubMed).
: "Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta." in: The Journal of biological chemistry, Vol. 272, Issue 48, pp. 30491-7, (1997) (PubMed).
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- AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
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别名
- AKT2
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途径
- PI3K-Akt Signaling, RTK signaling, AMPK Signaling, TLR signaling, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Hepatitis C, VEGF Signaling
抗原
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