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- 抗原 See all ODF2 抗体
- ODF2 (Outer Dense Fiber of Sperm Tails 2 (ODF2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ODF2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- This antibody was purified from monospecific antiserum by protein-A purified immunoaffinity chromatography. It is directed against, and shows specific reactivity for, human Cenexin-1 protein. A BLAST analysis was used to suggest cross-reactivity with Cenexin-1 from human, chimpanzee, mouse, rat, bovine sources based on 100% homology with the immunizing sequence. Reactivity with Cenexin-1 protein from other sources has not been determined.
- 产品特性
- This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. Cenexin-1 (ODF84) and cenexin-2 are splicing variants that are expressed from the same genetic locus Outer Dense Fiber protein 2 (ODF2) . Cenexin-1 and cenexin-2, regarded as centriolar proteins. Cenexin-1, a 93-kD variant of ODF2, is the major form of cennexin expressed in various somatic cells and tissues and associates with centrosomes. Cenexin-1 contains a unique C-terminal extension that appears to play a critical role in recruiting mitotic regulators such as polo-like kinase 1. In contrast, ODF2, a 70-kDa protein, is a major component of sperm tail cytoskeleton and abundantly expressed in testis. Additional evidence suggests that both of these proteins play important role in primary cilia formation. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. Cenexin-1 is one of the major outer dense fiber proteins. Multiple protein isoforms are encoded by transcript variants of the cenexin gene, however, not all isoforms and variants have been fully described.
- 纯化方法
- affinity purified
- 过滤
- Sterile filtered
- 免疫原
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This protein-A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a truncated recombinant protein hCenexin1.
Immunogen Type: RecombinantProtein - 亚型
- IgG
- Top Product
- Discover our top product ODF2 Primary Antibody
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anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) antibody
ODF2 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) (AA 706-804) antibodyODF2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) (AA 44-205) antibodyODF2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) (AA 630-829) antibodyODF2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) (pSer796) antibodyODF2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) antibodyODF2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) (Internal Region) antibodyVerified ODF2 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) (N-Term) antibodyODF2 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, Cow, 兔, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Outer Dense Fiber of Sperm Tails 2 (ODF2) (AA 218-267) antibodyODF2 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, Cow, 兔, Pig, 猴, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Anti-Cenexin-1 purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 93 kDa in size corresponding to Cenexin-1 by western blotting in the appropriate cell lysate or extract.
- 说明
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Gene Name: ODF2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.53 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
- 有效期
- 12 months
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- 抗原
- ODF2 (Outer Dense Fiber of Sperm Tails 2 (ODF2))
- 别名
- Cenexin-1 (ODF2 产品)
- 别名
- odf84 antibody, odf2/1 antibody, odf2/2 antibody, DKFZp469J0214 antibody, CT134 antibody, ODF2/1 antibody, ODF2/2 antibody, ODF84 antibody, si:dkey-228b2.4 antibody, AI848335 antibody, MMTEST29 antibody, outer dense fiber of sperm tails 2 antibody, outer dense fiber of sperm tails 2a antibody, outer dense fiber of sperm tails 2 L homeolog antibody, ODF2 antibody, odf2 antibody, odf2a antibody, odf2.L antibody, Odf2 antibody
- 背景
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This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Cenexin-1 (ODF84) and cenexin-2 are splicing variants that are expressed from the same genetic locus Outer Dense Fiber protein 2 (ODF2) . Cenexin-1 and cenexin-2, regarded as centriolar proteins. Cenexin-1, a 93-kD variant of ODF2, is the major form of cennexin expressed in various somatic cells and tissues and associates with centrosomes. Cenexin-1 contains a unique C-terminal extension that appears to play a critical role in recruiting mitotic regulators such as polo-like kinase 1. In contrast, ODF2, a 70-kDa protein, is a major component of sperm tail cytoskeleton and abundantly expressed in testis. Additional evidence suggests that both of these proteins play important role in primary cilia formation. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. Cenexin-1 is one of the major outer dense fiber proteins. Multiple protein isoforms are encoded by transcript variants of the cenexin gene; however, not all isoforms and variants have been fully described.
Synonyms: ODF84 antibody, Outer dense fiber of sperm tail 2 antibody, Cenexin1 variant 1 antibody, KKT 4 antibody - 基因ID
- 4957
- NCBI登录号
- NP_702915
- UniProt
- Q5BJF6
- 途径
- M Phase
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