RASGRP2 抗体 (N-Term)
(5 references)-
- 抗原 See all RASGRP2 抗体
- RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))
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抗原表位
- AA 14-42, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RASGRP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody recognizes Human RASGRP2 (N-term).
- 交叉反应 （详细）
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Species reactivity (expected):Mouse, Rat and Bovine.
Species reactivity (tested):Human. - 纯化方法
- Affinity Chromatography on Protein A
- 免疫原
- KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of Human RASGRP2. Genename: RASGRP2
- 亚型
- Ig Fraction
- Top Product
- Discover our top product RASGRP2 Primary Antibody
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anti-RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2) (AA 65-164) antibody
RASGRP2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D8 unconjugated
anti-RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2) (AA 7-34), (N-Term) antibodyRASGRP2 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB32230 unconjugated
anti-RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2) (AA 65-164) antibodyRASGRP2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2) (AA 1-671) antibodyRASGRP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2) antibodyRASGRP2 适用: 人 WB, IHC, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2) (AA 35-84) antibodyRASGRP2 适用: 人, 大鼠, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2) (AA 299-609) antibodyRASGRP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2) (AA 1-200) antibodyRASGRP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS, 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells." in: Journal of the American Society of Nephrology : JASN, Vol. 21, Issue 3, pp. 478-88, (2010) (PubMed).
: "Rap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-gamma1." in: The Journal of biological chemistry, Vol. 279, Issue 12, pp. 11875-81, (2004) (PubMed).
: "Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 20, pp. 12819-24, (2002) (PubMed).
: "A CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2." in: The Journal of biological chemistry, Vol. 276, Issue 27, pp. 25568-81, (2001) (PubMed).
: "Guanine nucleotide exchange factors CalDAG-GEFI and CalDAG-GEFII are colocalized in striatal projection neurons." in: The Journal of comparative neurology, Vol. 437, Issue 4, pp. 398-407, (2001) (PubMed).
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: "ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells." in: Journal of the American Society of Nephrology : JASN, Vol. 21, Issue 3, pp. 478-88, (2010) (PubMed).
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- 抗原
- RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))
- 别名
- RASGRP2 (RASGRP2 产品)
- 别名
- CALDAG-GEFI antibody, CDC25L antibody, xrasgrp2 antibody, RASGRP2 antibody, Caldaggef1 antibody, CalDAG-GEFI antibody, rasgrp2 antibody, RAS guanyl releasing protein 2 antibody, RAS guanyl releasing protein 2 (calcium and DAG-regulated) S homeolog antibody, RAS, guanyl releasing protein 2 antibody, RAS guanyl releasing protein 2 (calcium and DAG-regulated) L homeolog antibody, RASGRP2 antibody, rasgrp2.S antibody, Rasgrp2 antibody, rasgrp2.L antibody
- 背景
- The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.Synonyms: CDC25L, CalDAG-GEFI, Calcium and DAG-regulated guanine nucleotide exchange factor I, Cdc25-like protein, MCG7, RAS guanyl-releasing protein 2
- 分子量
- 75kd
- 基因ID
- 10235
- NCBI登录号
- NP_001092140
- 途径
- TCR Signaling
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