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PTPRN 抗体

PTPRN 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 8-00E-003 unconjugated
产品编号 ABIN954381
发货至: 中国
  • 抗原 See all PTPRN 抗体
    PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
    适用
    • 39
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    宿主
    • 49
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    • 1
    小鼠
    克隆类型
    • 52
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    单克隆
    标记
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    This PTPRN antibody is un-conjugated
    应用范围
    • 24
    • 22
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    • 13
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes PTPRN
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Protein A Chromatography
    免疫原
    Recombinant protein.
    克隆位点
    8-00E-003
    亚型
    IgG2a
    Top Product
    Discover our top product PTPRN Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS, pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))
    别名
    PTPRN (PTPRN 产品)
    别名
    IA-2 antibody, IA-2/PTP antibody, IA2 antibody, ICA512 antibody, R-PTP-N antibody, mIA-A antibody, mKIAA4064 antibody, Ia-2 antibody, fc43c04 antibody, ptprn antibody, wu:fc43c04 antibody, ia-2 antibody, ia2 antibody, ica512 antibody, r-ptp-n antibody, protein tyrosine phosphatase, receptor type N antibody, protein tyrosine phosphatase, receptor type, N antibody, protein tyrosine phosphatase, receptor type, Na antibody, protein tyrosine phosphatase, receptor type N L homeolog antibody, PTPRN antibody, Ptprn antibody, ptprna antibody, ptprn.L antibody
    背景
    IA-2, a R8 receptor protein tyrosine phosphatase, is one of the major autoantigens in type 1 diabetes. Autoantibodies against IA-2 have been detected in large numbers newly diagnosed patients with type 1 diabetes and appear to identify a subgroup of prediabetic subjects who rapidly progress to type 1 diabetes, however, IA-2 polymorphisms do not appear to be associated with type 1 diabetes. Three alternative spliced variants of IA-2 have been documented and alternative splicing of IA-2 gene has been suggested to be a permissive genetic mechanism for autoimmunity against the IA-2 type 1 diabetes autoantigen.Synonyms: ICA3, ICA512, Islet cell antigen 512, PTP IA-2, R-PTP-N, Receptor-type tyrosine-protein phosphatase-like N
    基因ID
    5798
    NCBI登录号
    NP_002837
    UniProt
    Q16849
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