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JNK 抗体 (AA 162-199)
MAPK8
适用: 人, 小鼠
WB, IHC (p), EIA
宿主: 兔
Polyclonal
unconjugated
JNK抗体详情
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抗原
See all JNK (MAPK8) 抗体
JNK (MAPK8)
(Mitogen-Activated Protein Kinase 8 (MAPK8))
抗原表位
All epitopes for JNK 抗体
AA 162-199
适用
All reactivities for JNK 抗体
人, 小鼠
宿主
All hosts for JNK 抗体
兔
克隆类型
All clonalities for JNK 抗体
多克隆
标记
All conjugates for JNK 抗体
This JNK antibody is un-conjugated
应用范围
All applications for JNK 抗体
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
特异性
This antibody recognizes Human and Mouse MAPK8 / JNK1 (Thr183/Tyr185).
纯化方法
Protein A column, followed by peptide affinity purification
免疫原
KLH conjugated synthetic peptide between 162-199 amino acids from human MAPK8 / JNK1
亚型
Ig Fraction
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Discover our top product MAPK8 Primary Antibody
Alternatives
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anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (pThr183), (pTyr185) antibody
MAPK8
适用: 人, 小鼠, 大鼠, 犬, 兔
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), ICC, IHC (fro)
宿主: 兔
Polyclonal
unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 201-300) antibody
MAPK8
适用: 人, 小鼠, 大鼠, 小鸡, 犬
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
anti-Mitogen-Activated Protein Kinase 8 (MAPK8) (AA 151-250) antibody
MAPK8
适用: 人, 小鼠, 大鼠, 小鸡, Pig
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
浓度
0.25 mg/mL
缓冲液
PBS containing 0.09 % (W/V) Sodium Azide as preservative
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
JNK目标详情
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抗原
JNK (MAPK8)
(Mitogen-Activated Protein Kinase 8 (MAPK8))
别名
MAPK8 / JNK1 (MAPK8 产品 )
别名
JNK antibody, JNK-46 antibody, JNK1 antibody, JNK1A2 antibody, JNK21B1/2 antibody, PRKM8 antibody, SAPK1 antibody, SAPK1c antibody, AI849689 antibody, Prkm8 antibody, BSK antibody, BSK/DJNK antibody, Bsk antibody, CG5680 antibody, D-JNK antibody, D-junk antibody, DBSK/JNK antibody, DJNK antibody, DJNK/bsk antibody, Dmel\\CG5680 antibody, JNK/SAPK antibody, Jnk antibody, Junk antibody, SAPKa antibody, c-Jun antibody, dJNK antibody, jnk antibody, T10F20.15 antibody, jnk1 antibody, sapk1 antibody, mapk8 antibody, zgc:112379 antibody, JNKb antibody, mapk8b antibody, mitogen-activated protein kinase 8 antibody, Stress-activated protein kinase jnk-1 antibody, basket antibody, Protein kinase superfamily protein antibody, mitogen-activated protein kinase 8 L homeolog antibody, mitogen-activated protein kinase 8b antibody, mitogen-activated protein kinase 8B-like antibody, MAPK8 antibody, jnk-1 antibody, Mapk8 antibody, bsk antibody, ATMPK8 antibody, mapk8.L antibody, mapk8b antibody, LOC109094263 antibody
背景
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.Synonyms: JNK-1, JNK-46, Mitogen-activated protein kinase 8, PRKM8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1
分子量
48296 Da
基因ID
5599
NCBI登录号
NP_002741
途径
MAPK Pathway , WNT signaling , TLR signaling , Fc-epsilon Receptor Signaling Pathway , Neurotrophin Signaling Pathway , Activation of Innate immune Response , Hepatitis C , Toll-Like Receptors Cascades , Signaling of Hepatocyte Growth Factor Receptor , S100 Proteins
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