JNK 抗体
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北京 101111
Quick Overview for JNK 抗体 (ABIN953306)
抗原
See all JNK (MAPK8) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes MAPK8 / JNK1
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Protein A Chromatography
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免疫原
- Recombinant protein.
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS, pH 7.2
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
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别名
- MAPK8 / JNK1
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背景
- JNK1, a MAPK type protein kinase, regulates cell apoptosis, differentiation and growth in response to growth factors, inflammatory cytokines and cellular stress. JNK1 is phosphorylated by MKK4/MAP2K4 and MKK7/MAP2K7. Activated JNK1 translocates to the nucleus where it phosphorylates transcription factors, including c-Jun, ATF2, ELK1, Jun-D and NFAT4. At least four alternatively spliced transcript variants encoding distinct isoforms, 384 and 427 amino acids, have been identified.Synonyms: JNK-1, JNK-46, Mitogen-activated protein kinase 8, PRKM8, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1
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基因ID
- 5599
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NCBI登录号
- NP_002741
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UniProt
- P45983
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途径
- MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
抗原
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