htatip2 antibody, MGC89074 antibody, HTATIP2 antibody, fb15b04 antibody, tip30 antibody, wu:fb15b04 antibody, CC3 antibody, SDR44U1 antibody, TIP30 antibody, AW111545 antibody, Cc3 antibody, Tip30 antibody, HIV-1 Tat interactive protein 2 antibody, HIV-1 Tat interactive protein 2 L homeolog antibody, HTATIP2 antibody, htatip2 antibody, Htatip2 antibody, htatip2.L antibody
物质类
Viral Protein
背景
Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.Synonyms: 30 kDa HIV-1 TAT-interacting protein, CC3, HIV-1 TAT-interactive protein 2, Oxidoreductase HTATIP2, TIP30