FBXW7 抗体 (AA 599-708)
Quick Overview for FBXW7 抗体 (AA 599-708) (ABIN952295)
抗原
See all FBXW7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 599-708
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特异性
- Recognizes Fbxw7
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Protein A Chromatography
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免疫原
- FBXW7 (NP_361014, 599 a.a. ~ 708 a.a) partial recombinant protein with GST tag.
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亚型
- IgG2a
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anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (C-Term) antibody
FBXW7 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 501-600) antibodyFBXW7 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-707) antibodyFBXW7 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D1 unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 1-627) antibodyFBXW7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 279-515) antibodyFBXW7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 1-707) antibodyFBXW7 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-707) antibodyFBXW7 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (C-Term) antibodyFBXW7 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 兔, 豚鼠, 马, 斑马鱼, Drosophila melanogaster, 猴, 非洲爪蟾, Hamster, Bat, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 251-300) antibodyFBXW7 适用: 小鼠, 大鼠, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-F-Box and WD Repeat Domain Containing 7 (FBXW7) (AA 599-708) antibodyFBXW7 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D1 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS, pH 7.2
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
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别名
- FBXW7
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背景
- Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin-E, MYC, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.Synonyms: Archipelago homolog, F-box and WD-40 domain-containing protein 7, F-box protein FBX30, F-box/WD repeat-containing protein 7, FBW7, FBX30, SEL-10, SEL10, hAgo, hCDC4
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基因ID
- 55294
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NCBI登录号
- NP_001013433
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UniProt
- Q969H0
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途径
- Notch Signaling, EGFR Signaling Pathway
抗原
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