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Desmoglein 1 抗体 (Internal Region)

DSG1 适用: 人 IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN951891
发货至: 中国
  • 抗原 See all Desmoglein 1 (DSG1) 抗体
    Desmoglein 1 (DSG1)
    抗原表位
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 86
    • 23
    • 11
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 56
    • 30
    • 1
    山羊
    克隆类型
    • 51
    • 36
    多克隆
    标记
    • 38
    • 9
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This Desmoglein 1 antibody is un-conjugated
    应用范围
    • 48
    • 27
    • 27
    • 21
    • 20
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    序列
    C-YTTSDTLKPS VHVHD
    特异性
    Recognizes Desmoglein 1 / DSG1
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide with sequence from the internal region of the protein sequence according to NP_001933.2. Genename: DSG1
    Top Product
    Discover our top product DSG1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Desmoglein 1 (DSG1)
    别名
    Desmoglein-1 (DSG1 产品)
    别名
    CDHF4 antibody, DG1 antibody, DSG antibody, PPKS1 antibody, SPPK1 antibody, DSG-1 antibody, DSG1 antibody, Dsg1b antibody, Dsg1c antibody, desmoglein 1 antibody, desmoglein 4 antibody, DSG1 antibody, DSG4 antibody, Dsg1 antibody
    背景
    Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. Desmoglein 1 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus. Desmoglein 1 is a 165kD glycoprotein that is a core component of the desmosome cell-cell junction between epithelial cells. Desmoglein 1 is synthesized in the suprabasal layer of the skin, and is vital to epidermal integrity.Synonyms: CDHF4, Cadherin family member 4, DG1, DGI, DSG1, Desmosomal glycoprotein 1, Pemphigus foliaceus antigen
    基因ID
    1828
    NCBI登录号
    NP_001933
    途径
    Cell-Cell Junction Organization
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