CXCR3 抗体 (Middle Region)
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- 抗原 See all CXCR3 抗体
- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
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抗原表位
- AA 147-175, Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CXCR3 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody recognizes Human CXCR3. Other species not tested.
- 纯化方法
- Affinity chromatography on Protein A
- 免疫原
- KLH conjugated synthetic peptide between 147-175 amino acids from the Central region of human CXCR3
- 亚型
- Ig Fraction
- Top Product
- Discover our top product CXCR3 Primary Antibody
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anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) antibody
CXCR3 适用: 人 FACS, WB, ELISA, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 5C10E6 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 301-367) antibodyCXCR3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (C-Term) antibodyVerified CXCR3 适用: 人 FACS, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-368) antibodyCXCR3 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) antibodyCXCR3 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 4-50) antibodyCXCR3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-100) antibodyCXCR3 适用: 人, 小鼠 FACS, WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 140-167) antibodyCXCR3 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal RB23384 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) antibody (FITC)GMP Grade CXCR3 适用: 人 FACS 宿主: 小鼠 Monoclonal 1C6 FITC
anti-Chemokine (C-X-C Motif) Receptor 3 (CXCR3) antibody (iFluor™647)GMP Grade CXCR3 适用: 人 FACS 宿主: 小鼠 Monoclonal 1C6 iFluor™647
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS, 0.09 % (W/V) Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
- 别名
- CD183 / CXCR3 (CXCR3 产品)
- 别名
- CD182 antibody, CD183 antibody, CKR-L2 antibody, CMKAR3 antibody, GPR9 antibody, IP10-R antibody, Mig-R antibody, MigR antibody, Cd183 antibody, Cmkar3 antibody, CXCR3 antibody, cxcr3 antibody, Gpr9 antibody, CXC-R3 antibody, CXCR-3 antibody, zgc:92301 antibody, sb:eu378 antibody, C-X-C motif chemokine receptor 3 antibody, chemokine (C-X-C motif) receptor 3 antibody, chemokine (C-X-C motif) receptor 3, tandem duplicate 2 antibody, chemokine (C-X-C motif) receptor 3, tandem duplicate 1 antibody, CXCR3 antibody, Cxcr3 antibody, cxcr3 antibody, cxcr3.2 antibody, cxcr3.1 antibody
- 背景
- This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed IP10 (interferon-g-inducible 10 kDa protein), Mig (monokine induced by interferon-g) and I-TAC (interferon-inducible T cell a-chemoattractant). IP10, Mig and I-TAC belong to the structural subfamily of CXC chemokines, in which a single amino acid residue separates the first two of four highly conserved Cys residues. Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Inhibition by Bordetella pertussis toxin suggests that heterotrimeric G protein of the Gi-subclass couple to this protein. Signal transduction has not been further analyzed but may include the same enzymes that were identified in the signaling cascade induced by other chemokine receptors. As a consequence of chemokine-induced cellular desensitization (phosphorylation-dependent receptor internalization), cellular responses are typically rapid and short in duration. Cellular responsiveness is restored after dephosphorylation of intracellular receptors and subsequent recycling to the cell surface. This gene is prominently expressed in in vitro cultured effector/memory T cells, and in T cells present in many types of inflamed tissues. In addition, IP10, Mig and I-TAC are commonly produced by local cells in inflammatory lesion, suggesting that this gene and its chemokines participate in the recruitment of inflammatory cells. Therefore, this protein is a target for the development of small molecular weight antagonists, which may be used in the treatment of diverse inflammatory diseases. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: CXC-R3, CXCR-3, G protein-coupled receptor 9, GPR9, IP-10 receptor, IP10 receptor, Interferon-inducible protein 10 receptor
- 分子量
- 40660 Da
- 基因ID
- 2833
- NCBI登录号
- NP_001136269
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