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CD32/CD16 抗体

CD32/CD16 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal KT1632 unconjugated
产品编号 ABIN951199
发货至: 中国
  • 抗原 See all CD32/CD16 products
    CD32/CD16
    适用
    小鼠
    宿主
    • 44
    • 1
    • 1
    大鼠
    克隆类型
    • 41
    • 1
    • 1
    单克隆
    标记
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD32/CD16 antibody is un-conjugated
    应用范围
    • 45
    • 8
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    纯化方法
    Protein G Chromatography
    克隆位点
    KT1632
    亚型
    IgG2a
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    CD32/CD16
    别名
    CD16/CD32 (CD32/CD16 产品)
    背景
    The lymphocyte Fc-gamma Receptors recognize the Fc portion of IgG, presented either as immune complexes or as free antibody. The different classes of receptors are distinct because of varying size, tissue distribution and affinity for IgGs. The Fc type II receptor is expressed on a wide variety of cells including B cells, hematopoietic cells, monocyte/macrophages, neutrophils, platelets, Langerhans cells, eosinophils, basophils, trophoblasts, and endothelial cells of the placenta. The Fc-gamma type III receptors are higher affinity than the type II and are expressed on macrophages, NK cells and neutrophils. Both types of receptors can be expressed on the same cell and in varying ratios. The receptors are constitutively expressed, although cytokines and lymphokines can modulate their expression. Besides identifying Fc-gammaR+ cells, monoclonal antibodies to the Fc-gammaII/III receptor have been used to block Fc receptor binding of IgG, Fcmediated signal transduction and effector functions, clearance of immune complexes and to attenuate infection by organisms dependent on Fc-gamma R for parasitic invasion.Synonyms: CD16a, FCG3, FCGR3A, Fc gamma receptor IIB, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, Fc-gamma-RIIB, FcR mouse Seroblock, FcRII, FcRIII, FcRIIIa, Fcgr2, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A, Low affinity immunoglobulin gamma Fc region receptor III-B, Ly-17
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