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ADIPOQ 抗体

ADIPOQ 适用: 小鼠 WB 宿主: 大鼠 Monoclonal 7J61 unconjugated
产品编号 ABIN950284
发货至: 中国
  • 抗原 See all ADIPOQ 抗体
    ADIPOQ (Adiponectin (ADIPOQ))
    适用
    • 136
    • 55
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    小鼠
    宿主
    • 120
    • 64
    • 6
    • 3
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    • 1
    • 1
    大鼠
    克隆类型
    • 130
    • 65
    单克隆
    标记
    • 113
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    This ADIPOQ antibody is un-conjugated
    应用范围
    • 119
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    Western Blotting (WB)
    特异性
    This antibody detects Mouse Adiponectin. It is crossreactive to Human Adiponectin protein in Western blotting.
    纯化方法
    Protein A/G Affinity Chromatography
    过滤
    0.2 μm filtered
    免疫原
    Purified Mouse Recombinant Adiponectin.
    克隆位点
    7J61
    亚型
    IgG2
    Top Product
    Discover our top product ADIPOQ Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 溶解方式
    Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL
    缓冲液
    0.2 μm filtered solution in PBS
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 months.
    有效期
    6 months
  • 抗原
    ADIPOQ (Adiponectin (ADIPOQ))
    别名
    Adiponectin (ADIPOQ 产品)
    别名
    ADP antibody, DCAF9 antibody, 6720489L24Rik antibody, 9330209L04Rik antibody, Adp antibody, Mamdc1 antibody, RNSVSP4U antibody, SVSIV1 antibody, Svp4 antibody, ACDC antibody, ACRP30 antibody, ADIPQTL1 antibody, ADPN antibody, APM-1 antibody, APM1 antibody, GBP28 antibody, apM-1 antibody, 30kDa antibody, APN antibody, Acdc antibody, Acrp30 antibody, Ad antibody, adipo antibody, apM1 antibody, ADN antibody, acrpl antibody, adipo-b antibody, adipoql antibody, zgc:153584 antibody, adipoq antibody, WD and tetratricopeptide repeats 1 antibody, MAM domain containing glycosylphosphatidylinositol anchor 2 antibody, seminal vesicle secretory protein 4 antibody, adiponectin, C1Q and collagen domain containing antibody, adiponectin, C1Q and collagen domain containing, b antibody, adiponectin, C1Q and collagen domain containing L homeolog antibody, WDTC1 antibody, Mdga2 antibody, Svs4 antibody, ADIPOQ antibody, Adipoq antibody, adipoqb antibody, adipoq.L antibody
    背景
    Adiponectin, also known as Acrp30, is an adipocyte-derived protein with wide ranging paracrine and endocrine effects on metabolism and inflammation. It promotes adipocyte differentiation, fatty acid catabolism, and insulin sensitivity, and is negatively correlated with obesity, type 2 diabetes, and atherogenesis. In this context, adiponectin is an antiinflammatory agent, but it exerts proinflammatory effects in nonmetabolic disorders such as rheumatoid arthritis and inflammatory bowel disease. Adiponectin interacts with the receptors AdipoR1 and AdipoR2, calreticulin, and Cadherin13/ T-Cadherin, as well as with several growth factors. Mature mouse adiponectin consists of a 66 amino acid (aa) N-terminal collagenous region and a 137 aa C terminal C1q like globular domain which can be cleaved by a leukocytederived elastase. Mature mouse adiponectin shares 83 % and 91 % amino acid (aa) sequence identity with human and rat adiponectin, respectively. Adiponectin associates into trimers that may assemble into medium molecular weight (MMW) hexamers and then into >300 kDa high molecular weight (HMW) oligomers. The glycosylation of four hydroxylated lysine residues in the collagenous domain is required for the intracellular formation of HMW complexes. The various multimeric forms of adiponectin exhibit distinct tissue specific and gender specific profiles and activities.Synonyms: 30 kDa adipocyte complement-related protein, ACDC, ACRP30, ADIPOQ, APM1, Adipocyte, Adipocyte complement-related 30 kDa protein, Adipose most abundant gene transcript 1 protein, C1q and collagen domain-containing protein, GBP28, Gelatin-binding protein
    基因ID
    11450
    NCBI登录号
    NP_033735
    UniProt
    Q60994
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