DDR1 抗体 (AA 602-681)
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北京 101111
Quick Overview for DDR1 抗体 (AA 602-681) (ABIN931384)
抗原
See all DDR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 602-681
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免疫原
- DDR1 antibody was raised in Mouse using a purified recombinant fragment of DDR1(aa602-681) expressed in E. coli as the immunogen.
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亚型
- IgG1
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应用备注
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ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term storage. Store at -20 °C for long term storage.
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- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
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别名
- DDR1
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背景
- DDR1 is a Receptor Tyrosine Kinase that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested. In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. Synonyms: Monoclonal DDR1 antibody, Anti-DDR1 antibody, CAK antibody, cell adhesion kinase antibody, discoidin domain receptor 1 antibody, Drd1 antibody, EDDR1 antibody, epithelial discoidin domain receptor 1 antibody, mammarian carcinoma kinase 10 antibody, MCK10 antibody, nep antibody, neuroepithelium antibody.
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途径
- RTK signaling, Smooth Muscle Cell Migration
抗原
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