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DDR1 抗体 (AA 602-681)

This anti-DDR1 antibody is a 小鼠 单克隆 antibody detecting DDR1 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN931384
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for DDR1 抗体 (AA 602-681) (ABIN931384)

抗原

See all DDR1 抗体
DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DDR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

2G4E12
  • 抗原表位

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    AA 602-681

    免疫原

    DDR1 antibody was raised in Mouse using a purified recombinant fragment of DDR1(aa602-681) expressed in E. coli as the immunogen.

    亚型

    IgG1
  • 应用备注

    ELISA: 1:10,000, WB: 1:500-1:2000
    Optimal conditions should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C for short term storage. Store at -20 °C for long term storage.
  • 抗原

    DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

    别名

    DDR1

    背景

    DDR1 is a Receptor Tyrosine Kinase that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested. In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. Synonyms: Monoclonal DDR1 antibody, Anti-DDR1 antibody, CAK antibody, cell adhesion kinase antibody, discoidin domain receptor 1 antibody, Drd1 antibody, EDDR1 antibody, epithelial discoidin domain receptor 1 antibody, mammarian carcinoma kinase 10 antibody, MCK10 antibody, nep antibody, neuroepithelium antibody.

    途径

    RTK signaling, Smooth Muscle Cell Migration
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