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CD22 抗体 (C-Term)

Name: CD22 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN929370
Availability: OutOfStock

CD22 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

CD22 antibody used at 0. (CD22 抗体 (C-Term))

1 image

产品编号 ABIN929370

发货至: 中国

Datasheet as PDF

抗原 See all CD22 抗体

CD22 (CD22 Molecule (CD22))
抗原表位
16

11

6

5

4

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
148

48

24

5

3

2

2

1
人
宿主
96

61

13
兔
Compatible Secondaries
克隆类型
118

54
多克隆
标记
80

14

12

10

6

5

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This CD22 antibody is un-conjugated
应用范围
107

69

44

37

37

16

12

11

11

6

5

4

3

3

3

1

1

1

1

1
Western Blotting (WB)

纯化方法

Purified

免疫原

CD22 antibody was raised in rabbit using the C terminal of CD22 as the immunogen

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anti-CD22 Molecule (CD22) (AA 708-847) antibody
CD22 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

说明

CD22 Blocking Peptide, catalog no. 33R-10236, is also available for use as a blocking control in assays to test for specificity of this CD22 antibody

限制

仅限研究用
状态

Lyophilized

浓度

Lot specific

缓冲液

Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

注意事项

Avoid repeated freeze/thaw cycles.

储存条件

4 °C/-20 °C

储存方法

Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
抗原

CD22 (CD22 Molecule (CD22))

别名

CD22 (CD22 产品)

别名

A530093D23 antibody, Lyb-8 antibody, Lyb8 antibody, SIGLEC-2 antibody, SIGLEC2 antibody, siglec-2 antibody, CD22 antigen antibody, CD22 molecule antibody, Cd22 antibody, CD22 antibody

背景

CD22 mediates B-cell B-cell interactions. CD22 may be involved in the localization of B-cells in lymphoid tissues. CD22 binds sialylated glycoproteins, one of which is CD45. CD22 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response CD22 seems to be involved in regulation of B-cell antigen receptor signaling. CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Synonyms: Polyclonal CD22 antibody, Anti-CD22 antibody, CD22 molecule antibody, FLJ22814 antibody, MGC130020 antibody, SIGLEC-2 antibody, SIGLEC2 antibody.