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COCH 抗体 (C-Term)

COCH 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN929279
发货至: 中国
  • 抗原 See all COCH 抗体
    COCH (Cochlin (COCH))
    抗原表位
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 48
    • 13
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 46
    • 2
    克隆类型
    • 48
    多克隆
    标记
    • 21
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COCH antibody is un-conjugated
    应用范围
    • 37
    • 27
    • 16
    • 13
    • 3
    • 2
    • 2
    Western Blotting (WB)
    纯化方法
    Purified
    免疫原
    COCH antibody was raised in rabbit using the C terminal of COCH as the immunogen
    Top Product
    Discover our top product COCH Primary Antibody
  • 应用备注
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    COCH Blocking Peptide, catalog no. 33R-9444, is also available for use as a blocking control in assays to test for specificity of this COCH antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原
    COCH (Cochlin (COCH))
    别名
    COCH (COCH 产品)
    别名
    AW122937 antibody, Coch-5B2 antibody, D12H14S564E antibody, COCH-5B2 antibody, COCH5B2 antibody, DFNA9 antibody, cochlin antibody, Coch antibody, COCH antibody
    背景
    The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. Synonyms: Polyclonal COCH antibody, Anti-COCH antibody, coagulation factor C homolog, cochlin, Limulus polyphemus antibody, COCH-5B2 antibody, COCH5B2 antibody, DFNA9 antibody.
    途径
    Sensory Perception of Sound
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