LRP8 抗体 (Middle Region)
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- 抗原 See all LRP8 抗体
- LRP8 (Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))
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抗原表位
- Middle Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LRP8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 小鼠
- 纯化方法
- Purified
- 免疫原
- Lrp8 antibody was raised in rabbit using the middle region of Lrp8 as the immunogen
- Top Product
- Discover our top product LRP8 Primary Antibody
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- 应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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Lrp8 Blocking Peptide, catalog no. 33R-1206, is also available for use as a blocking control in assays to test for specificity of this Lrp8 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- 抗原
- LRP8 (Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8))
- 别名
- Lrp8 (LRP8 产品)
- 别名
- LRP8 antibody, APOER2 antibody, HSZ75190 antibody, LRP-8 antibody, MCI1 antibody, 4932703M08Rik antibody, AA921429 antibody, AI848122 antibody, ApoER2 antibody, Lr8b antibody, LR8B antibody, LDL receptor related protein 8 antibody, low density lipoprotein receptor-related protein 8, apolipoprotein e receptor antibody, LRP8 antibody, Lrp8 antibody
- 背景
- Lrp8 is the cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development. Synonyms: Polyclonal Lrp8 antibody, Anti-Lrp8 antibody, low density lipoprotein receptor-related protein 8, apolipoprotein e receptor antibody, 4932703M08Rik antibody, AA921429 antibody, AI848122 antibody, Lr8b antibody, apoER2 antibody.
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