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REST 抗体 (Middle Region)

REST 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN927729
发货至: 中国
  • 抗原 See all REST 抗体
    REST (RE1-Silencing Transcription Factor (REST))
    抗原表位
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 47
    • 10
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 46
    • 1
    克隆类型
    • 46
    • 1
    多克隆
    标记
    • 26
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This REST antibody is un-conjugated
    应用范围
    • 32
    • 22
    • 10
    • 8
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    小鼠
    纯化方法
    Purified
    免疫原
    Rest antibody was raised in rabbit using the middle region of Rest as the immunogen
    Top Product
    Discover our top product REST Primary Antibody
  • 应用备注
    Optimal conditions should be determined by the investigator.
    说明

    Rest Blocking Peptide, catalog no. 33R-1402, is also available for use as a blocking control in assays to test for specificity of this Rest antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原
    REST (RE1-Silencing Transcription Factor (REST))
    别名
    Rest (REST 产品)
    别名
    NRSF antibody, XBR antibody, 2610008J04Rik antibody, AA407358 antibody, xbr antibody, nrsf antibody, rest antibody, resta antibody, REST antibody, RE1 silencing transcription factor antibody, RE1-silencing transcription factor antibody, RE1-silencing transcription factor S homeolog antibody, REST antibody, Rest antibody, rest.S antibody, rest antibody, LOC615792 antibody
    背景
    Rest is a transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Rest restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Rest mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Synonyms: Polyclonal Rest antibody, Anti-Rest antibody, RE1-silencing transcription factor antibody, 2610008J04Rik antibody, AA407358 antibody, MGC150099 antibody, NRSF antibody.
    途径
    Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
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