REST 抗体 (Middle Region)
-
- 抗原 See all REST 抗体
- REST (RE1-Silencing Transcription Factor (REST))
-
抗原表位
- Middle Region
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This REST antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 交叉反应
- 小鼠
- 纯化方法
- Purified
- 免疫原
- Rest antibody was raised in rabbit using the middle region of Rest as the immunogen
- Top Product
- Discover our top product REST Primary Antibody
-
-
- 应用备注
- Optimal conditions should be determined by the investigator.
- 说明
-
Rest Blocking Peptide, catalog no. 33R-1402, is also available for use as a blocking control in assays to test for specificity of this Rest antibody
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
-
- 抗原
- REST (RE1-Silencing Transcription Factor (REST))
- 别名
- Rest (REST 产品)
- 别名
- NRSF antibody, XBR antibody, 2610008J04Rik antibody, AA407358 antibody, xbr antibody, nrsf antibody, rest antibody, resta antibody, REST antibody, RE1 silencing transcription factor antibody, RE1-silencing transcription factor antibody, RE1-silencing transcription factor S homeolog antibody, REST antibody, Rest antibody, rest.S antibody, rest antibody, LOC615792 antibody
- 背景
- Rest is a transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Rest restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Rest mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Synonyms: Polyclonal Rest antibody, Anti-Rest antibody, RE1-silencing transcription factor antibody, 2610008J04Rik antibody, AA407358 antibody, MGC150099 antibody, NRSF antibody.
- 途径
- Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
-