IGF1R 抗体 (Middle Region)
Quick Overview for IGF1R 抗体 (Middle Region) (ABIN926846)
抗原
See all IGF1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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交叉反应
- 小鼠, 大鼠, 猪, 牛, 小鸡, 斑马鱼, Frog
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纯化方法
- Purified
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免疫原
- IGF1 R antibody was raised in rabbit using the middle region of IGF1 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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IGF1R Blocking Peptide, (ABIN937530), is also available for use as a blocking control in assays to test for specificity of this IGF1R antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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别名
- IGF1R
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背景
- This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Synonyms: Polyclonal IGF1R antibody, Anti-IGF1R antibody, insulin-like growth factor 1 receptor antibody, CD221 antibody, IGFIR antibody, JTK13 antibody, MGC142170 antibody, MGC142172 antibody, MGC18216 antibody.
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途径
- RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
抗原
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