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PCNA 抗体 (C-Term)

This anti-PCNA antibody is a 兔 多克隆 antibody detecting PCNA in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 犬, 斑马鱼, Cow 和 非洲爪蟾.
产品编号 ABIN925999
发货至: 中国

Quick Overview for PCNA 抗体 (C-Term) (ABIN925999)

抗原

See all PCNA 抗体
PCNA (Proliferating Cell Nuclear Antigen (PCNA))

适用

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人, 小鼠, 大鼠, 犬, 斑马鱼, Cow, 非洲爪蟾

宿主

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克隆类型

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多克隆

标记

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This PCNA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    交叉反应

    小鼠, 大鼠, 犬, 牛, Frog, 斑马鱼

    免疫原

    PCNA antibody was raised in rabbit using the C terminal of PCNA as the immunogen
  • 应用备注

    WB: 1.25 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    PCNA Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this PCNA antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原

    PCNA (Proliferating Cell Nuclear Antigen (PCNA))

    别名

    PCNA

    背景

    PCNA is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. Synonyms: Polyclonal PCNA antibody, Anti-PCNA antibody, proliferating cell nuclear antigen antibody, MGC8367 antibody.

    途径

    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
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