PCNA 抗体 (C-Term)
Quick Overview for PCNA 抗体 (C-Term) (ABIN925999)
抗原
See all PCNA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - C-Term
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交叉反应
 - 小鼠, 大鼠, 犬, 牛, Frog, 斑马鱼
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免疫原
 - PCNA antibody was raised in rabbit using the C terminal of PCNA as the immunogen
 
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应用备注
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                        WB: 1.25 µg/mL
Optimal conditions should be determined by the investigator. - 
                                            
说明
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PCNA Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this PCNA antibody
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限制
 - 仅限研究用
 
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状态
 - Lyophilized
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浓度
 - Lot specific
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缓冲液
 - Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
 - Avoid repeated freeze/thaw cycles.
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储存条件
 - 4 °C/-20 °C
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储存方法
 - Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
 
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- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
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别名
 - PCNA
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背景
 - PCNA is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. Synonyms: Polyclonal PCNA antibody, Anti-PCNA antibody, proliferating cell nuclear antigen antibody, MGC8367 antibody.
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途径
 - Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
 
抗原
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