FAS 抗体 (FITC)
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北京 101111
Quick Overview for FAS 抗体 (FITC) (ABIN920646)
抗原
See all FAS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Reacts specifically with the human Fas antigen, although the epitope has not been mapped. Binds both the soluble and membrane-bound forms of Fas. Does not react with mouse or gibbon Fas. Recognizes activated T-cells and a subpopulation of B-cells. The cell-surface Fas antigen is a 48 kDa transmembrane protein that can mediate apoptosis/programmed cell death and belongs to the nerve growth factor (NGF)/tumor necrosis factor (TNF) receptor superfamily. The human Fas antigen is expressed in various human cells, including activated peripheral T and B lymphocytes, Various tumor cell lines, leukemic T cells, and myeloid cells. It is also differentially expressed on human thymocytes during thymic maturation.
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产品特性
- Mouse myeloma (P3.X63.Ag8.653) x immunized mouse (Balb/c) spleen cells.
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纯化方法
- Purified by protein A chromatography
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纯度
- > 95 % by SDS-PAGE.
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免疫原
- Human B lymphoblast cell line SKW6.4 cell surface molecules
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亚型
- IgG1
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anti-TNF Receptor Superfamily, Member 6 (FAS) antibody
FAS 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 150-250) antibodyFAS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) antibodyFAS 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 4F8H6 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 87-109), (N-Term) antibodyFAS 适用: 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 22-172) antibodyFAS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 22-169) antibodyFAS 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 21-170) antibodyFAS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 1-335) antibodyFAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1B6 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibodyFAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 5B4 unconjugated
anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibodyFAS 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2G3 unconjugated
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应用备注
- Immunohistochemistry on cryostat sections and on cytospin preparations. Not suitable for use on paraffin sections. Flow Cytometry: Use at 1:20 dilution (as determined on SKW6.4 cells.
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限制
- 仅限研究用
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缓冲液
- FITC-labeled antibody in 1 ml PBS, pH 7.4 with 1% BSA and 0.02% NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- FAS (TNF Receptor Superfamily, Member 6 (FAS))
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别名
- Fas
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背景
- Monoclonal antibody recognizing Fas protein, FITC-labeled for simplified flow cytometry procedures. Clone Apo-1-1 is an IgG1 isotype switch variant of the IgG3 clone APO-1-3 (Cat. No. MC-095).
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途径
- p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
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