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FAS 抗体 (FITC)

FAS 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal APO-1-1 FITC
产品编号 ABIN920646
发货至: 中国
  • 抗原 See all FAS 抗体
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
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    小鼠
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    单克隆
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    This FAS antibody is conjugated to FITC
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (IHC)
    特异性
    Reacts specifically with the human Fas antigen, although the epitope has not been mapped. Binds both the soluble and membrane-bound forms of Fas. Does not react with mouse or gibbon Fas. Recognizes activated T-cells and a subpopulation of B-cells. The cell-surface Fas antigen is a 48 kDa transmembrane protein that can mediate apoptosis/programmed cell death and belongs to the nerve growth factor (NGF)/tumor necrosis factor (TNF) receptor superfamily. The human Fas antigen is expressed in various human cells, including activated peripheral T and B lymphocytes, Various tumor cell lines, leukemic T cells, and myeloid cells. It is also differentially expressed on human thymocytes during thymic maturation.
    产品特性
    Mouse myeloma (P3.X63.Ag8.653) x immunized mouse (Balb/c) spleen cells.
    纯化方法
    Purified by protein A chromatography
    纯度
    > 95 % by SDS-PAGE.
    免疫原
    Human B lymphoblast cell line SKW6.4 cell surface molecules
    克隆位点
    APO-1-1
    亚型
    IgG1
    Top Product
    Discover our top product FAS Primary Antibody
  • 应用备注
    Immunohistochemistry on cryostat sections and on cytospin preparations. Not suitable for use on paraffin sections. Flow Cytometry: Use at 1:20 dilution (as determined on SKW6.4 cells.
    限制
    仅限研究用
  • 缓冲液
    FITC-labeled antibody in 1 ml PBS, pH 7.4 with 1% BSA and 0.02% NaN3.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    别名
    Fas (FAS 产品)
    背景
    Monoclonal antibody recognizing Fas protein, FITC-labeled for simplified flow cytometry procedures. Clone Apo-1-1 is an IgG1 isotype switch variant of the IgG3 clone APO-1-3 (Cat. No. MC-095).
    途径
    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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