FAM21C 抗体 (AA 1201-1318) (Cy7)
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- 抗原 See all FAM21C 抗体
- FAM21C (Family with Sequence Similarity 21, Member C (FAM21C))
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抗原表位
- AA 1201-1318
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FAM21C antibody is conjugated to Cy7
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Cow,Pig,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human FAM21C
- 亚型
- IgG
- Top Product
- Discover our top product FAM21C Primary Antibody
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anti-Family with Sequence Similarity 21, Member C (FAM21C) (AA 1-283) antibody
FAM21C 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- FAM21C (Family with Sequence Similarity 21, Member C (FAM21C))
- 别名
- FAM21C (FAM21C 产品)
- 别名
- Fam21 antibody, NP61201 antibody, FAM21A antibody, VPEF antibody, A130095H06 antibody, C530005J20Rik antibody, D6Wsu116e antibody, fam21c antibody, wu:fb78c06 antibody, zgc:153646 antibody, WASH complex subunit 2C antibody, WASH complex subunit 2 antibody, family with sequence similarity 21, member C antibody, Washc2c antibody, WASHC2C antibody, Washc2 antibody, washc2c antibody
- 背景
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Synonyms: FAM21A, Family with sequence similarity 21 member C, Hypothetical protein LOC253725, KIAA0592, Protein FAM21C, FA21C_HUMAN.
Background: Playing a essential role in the fission of tubules that serve as transport intermediates during endosome sorting, the WASH complex is present at the surface of endosomes and functions to recruit and activate the Arp2/3 complex for induction of actin polymerization. FAM21, Putative WASH complex subunit FAM21, is a component of the WASH complex. Having undergone evolutionary duplication, four highly homologous family members exist including FAM21A, FAM21B, FAM21C and FAM21D. FAM21 links the WASH complex to endosomes and is required for WASM-dependent retromer-mediated sorting. Also, by directly interacting with CapZ, FAM21 inhibits its anti-capping activity, thereby regulating actin dynamics.
- 基因ID
- 253725
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