S1PR1 抗体 (PE-Cy5.5)
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- 抗原 See all S1PR1 抗体
- S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This S1PR1 antibody is conjugated to PE-Cy5.5
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human S1P1
- 亚型
- IgG
- Top Product
- Discover our top product S1PR1 Primary Antibody
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anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (C-Term) antibody
S1PR1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) antibodyS1PR1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8E4H5 unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 51-150) antibodyS1PR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 311-382) antibodyS1PR1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 1-47) antibodyS1PR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E12 unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) antibodyS1PR1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1E3H5 unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 1-47) antibodyS1PR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F11 unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (Ser311) antibodyS1PR1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (AA 1-382) antibodyS1PR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingosine-1-Phosphate Receptor 1 (S1PR1) (Internal Region) antibodyS1PR1 适用: 人, 大鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
- 别名
- S1P1 (S1PR1 产品)
- 背景
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Synonyms: EDG1, S1P1, CD363, ECGF1, EDG-1, CHEDG1, D1S3362, Sphingosine 1-phosphate receptor 1, S1P receptor 1, Endothelial differentiation G-protein coupled receptor 1, Sphingosine 1-phosphate receptor Edg-1, S1P receptor Edg-1, S1PR1
Background: G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. Plays an important role in the regulation of sprouting angiogenesis and vascular maturation. Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development. Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs. Plays a role in the migration of osteoclast precursor cells, the regulation of bone mineralization and bone homeostasis (By similarity). Plays a role in responses to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury.
- 分子量
- 44kDa
- 基因ID
- 1901
- UniProt
- P21453
- 途径
- Signaling Events mediated by VEGFR1 and VEGFR2
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