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S1PR1 抗体 (AA 311-382)

S1PR1 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7170565
发货至: 中国
  • 抗原 See all S1PR1 抗体
    S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
    抗原表位
    • 15
    • 8
    • 7
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    • 2
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    AA 311-382
    适用
    • 88
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    • 45
    • 8
    • 4
    • 3
    • 3
    • 3
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    • 1
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    宿主
    • 86
    • 8
    克隆类型
    • 76
    • 18
    多克隆
    标记
    • 52
    • 5
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    • 2
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    This S1PR1 antibody is un-conjugated
    应用范围
    • 71
    • 37
    • 15
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    • 11
    • 8
    • 4
    • 3
    • 3
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Sphingosine 1-phosphate receptor 1 protein (311-382AA)
    亚型
    IgG
    Top Product
    Discover our top product S1PR1 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    S1PR1 (Sphingosine-1-Phosphate Receptor 1 (S1PR1))
    别名
    S1PR1 (S1PR1 产品)
    别名
    CD363 antibody, CHEDG1 antibody, D1S3362 antibody, ECGF1 antibody, EDG-1 antibody, EDG1 antibody, S1P1 antibody, AI849002 antibody, Edg1 antibody, Lpb1 antibody, S1p antibody, S1p1 antibody, S1P receptor 1 antibody, S1P receptor Edg-1 antibody, edg1 antibody, etID43307.22 antibody, s1p1 antibody, wu:fb98f05 antibody, s1pr1 antibody, xts1p1 antibody, sphingosine-1-phosphate receptor 1 antibody, sphingosine-1-phosphate receptor 1 L homeolog antibody, S1PR1 antibody, S1pr1 antibody, s1pr1 antibody, s1pr1.L antibody
    背景

    Background: G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. Plays an important role in the regulation of sprouting angiogenesis and vascular maturation. Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development. Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs. Plays a role in the migration of osteoclast precursor cells, the regulation of bone mineralization and bone homeostasis (By similarity). Plays a role in responses to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury.

    Aliases: CD363 antibody, CHEDG 1 antibody, CHEDG1 antibody, D1S3362 antibody, ECGF 1 antibody, ECGF1 antibody, EDG 1 antibody, EDG1 antibody, endothelial differentiation G protein coupled receptor 1 antibody, Endothelial differentiation G-protein coupled receptor 1 antibody, Endothelial differentiation sphingolipid G protein coupled receptor 1 antibody, FLJ58121 antibody, G protein coupled sphingolipid receptor antibody, g protein-coupled receptor edg-1 antibody, S1P receptor 1 antibody, S1P receptor Edg 1 antibody, S1P receptor Edg-1 antibody, S1P receptor Edg1 antibody, S1P(1) receptor antibody, S1P1 antibody, s1pr1 antibody, S1PR1_HUMAN antibody, sphingolipid g-protein-coupled receptor 1 antibody, Sphingosine 1 phosphate receptor Edg 1 antibody, Sphingosine 1 phosphate receptor EDG1 antibody, sphingosine 1- phosphate receptor 1 antibody, Sphingosine 1-phosphate receptor 1 antibody, Sphingosine 1-phosphate receptor Edg-1 antibody, Sphingosine 1phosphate receptor type 1 S1P1 antibody

    UniProt
    P21453
    途径
    Signaling Events mediated by VEGFR1 and VEGFR2
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